Résultats de la recherche - 22 results

Novel prediction models for genotoxicity based on biomarker genes in human HepaRG™ cells.

DNA microarray profiles of 24 (non-)genotoxic reference chemicals covering different modes of action in metabolically competent human HepaRG™ cells. In the present study, new prediction models for ...

NextGEM: Next-Generation Integrated Sensing and Analytical System for Monitoring and Assessing Radiofrequency Electromagnetic Field Exposure and Health.

Colussi, Loek; Pruppers, Mathieu; Baaken, Dan; Bogdanova, Anna Source: Int J Environ Res Public Health, Volume 20, Issue 12 (2023) Keywords: Cell Phone Electromagnetic Fields environmental exposure Humans ...

Development, Validation and Application of a Targeted LC-MS Method for Quantification of Microcystins and Nodularin: Towards a Better Characterization of Drinking Water

(PPIIA), disrupting cell growth and metabolism [15,16]. When ingested, these toxins are transported by the bile salts to the liver, potentially causing liver damage [17,18,19]. Health Topics:  Food ...

Confronting Risk of Bias in RF Bioeffects Research. Comments on Two Papers by Vijayalaxmi and Prihoda

https://doi.org/10.1667/ RR15478.1 In two meritorious published articles (1, 2), Vijayalaxmi and Prihoda reviewed 225 published laboratory studies with a total of 2,160 individual tests on genetic damage to mammalian cells ...

Multivalent binding of herpesvirus to living cells is tightly regulated during infection.

the cell surface. While multiple parallel interactions would allow strong virus attachment, a low number of bonds could be preferred to allow lateral diffusion toward specific receptors and to promote ...

Genome Editing in Agriculture: Methods, Applications, and Governance—A paper in the series on The Need for Agricultural Innovation to Sustainably Feed the World by 2050

(CAST), Volume 60, Issue 60 (2018) Abstract: Genome editing is the process of making precise, targeted sequence changes in the deoxyribonucleic acid of living cells and organisms. Recent advances have made ...

A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment

for pharmaceutical, chemical, and consumer products, as afflicted compounds have to be (prematurely) abandoned or further tested on animals. Using the metabolically competent human HepaRG ™ cell line and toxicogenomics ...

Genetic damage in humans exposed to extremely low-frequency electromagnetic fields.

i.e. increased cytogenetic damage in peripheral blood lymphocytes or buccal cells of ELF- MF-exposed subjects. This is important given the established link between observed cytogenetic damage in cells of ...

The Cytome Assay as a Tool to Investigate the Possible Association Between Exposure to Extremely Low Frequency Magnetic Fields and an Increased Risk for Alzheimer's Disease.

Keywords: Apoptosis Carcinoma Cell Line, Tumor Chromosome Aberrations Cytokinesis Dose-Response Relationship, Radiation Humans magnetic fields Risk Factors Abstract: Exposure to extremely low frequency ...

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