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Résultats de la recherche - 13 results

A Transcriptomic Biomarker to Classify Chemical-Induced Histone Deacetylase Inhibition in Human HepaRGTM Cells

Science Forum, Ottawa, Canada (2024) Keywords: HepaRG cells histone deacetylase inhibition transcriptomic biomarker Health Topics:  Health and environment Santé et environnement Gezondheid en milieu ...

The GENOMARK transcriptomic biomarker demonstrates a high predictivity for genotoxic hazards and utility in potency ranking in human HepaRGTM cells

Publication Type: Scientific poster, presentation or proceeding Authors: Anouck Thienpont; Eunnara Cho; Andrew Williams; Matthew Meier; Carole Yauk; Vera Rogiers; Tamara Vanhaecke; Birgit Mertens Source: EEMGS meeting, Malaga, Spain (2023) Keywords: bench ...

The GENOMARK biomarker inhuman HepaRGTM cells: a new approach methodology for genotoxicity assessment

Publication Type: Scientific poster, presentation or proceeding Authors: Anouck Thienpont; Stefaan Verhulst; Leo van Grunsven; Vera Rogiers; Tamara Vanhaecke; Birgit Mertens Source: SaferWorldByDesign webinar, Online (2023) Keywords: genotoxicity NAM tran ...

In vitro model to study the endocrine disrupting activity of migration products from plastic food contact materials

(these) activity(ies) will be explored using cell based transactivational assays also named “reporter gene assays. The MCF7 recombinant cells used here are genitically modified cells containing the firefly ...

Scientific opinion on the risk for public and animal health related to the presence of sterigmatocystin in food and feed

3335, Parma, p.81 (2013) Accession Number: NA Keywords: Absence adverse effects Aflatoxins ALL an Animal Animals approach approaches assessment cells contaminant contaminants data detection dietary ...

Genotoxicity of water extracts from hypoxis species

and H. acuminata and from a commercial preparation thereof using the neutral red uptake (NRU) assay, the alkaline comet assay and the cytome assay in human hepatoma HepG2 cells. The relative ...

Combretum microphyllum and Leucospermum erubescens inhibit the genotoxic effects of 4-NQO, MMC and EMS in vitro

Pharmacology (ACP2012), University of Pretoria- Dept. of Pharmacology, Issue Dept.Pharmacology,Univertsity of Pretoria, Pretoria (2012) Keywords: Activity Africa ALL an AS Belgium Brussels cancer cells Clinical ...

Testing chemical agents with the cytokinesis-block micronucleus cytome assay.

Publication Type: Peer reviewed scientific article Authors: Annemarie Maes; Anthonissen, R; Luc Verschaeve Source: Folia Biol (Praha), Volume 58, Issue 5 (2012) Keywords: Cell Line Cytokinesis ...

Characterization of new Alternaria alternata--specific rat monoclonal antibodies.

Immunosorbent Assay Female rats Abstract: In this study, three different rat hybridoma cell lines secreting monoclonal antibodies (mAbs) recognizing the spores from Alternaria alternata, a plant pathogenic ...

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