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Résultats de la recherche - 187 results

Pharmacokinetics of Oral Rebaudioside A in Patients with Type 2 Diabetes Mellitus and Its Effects on Glucose Homeostasis: A Placebo-Controlled Crossover Trial

observed for rebaudioside A in mice, they have been attributed to the metabolites steviol and steviol glucuronide. We aimed to characterize the pharmacokinetic and pharmacodynamic properties of rebaudioside ...

Update of the risk assessment of hexabromocyclododecanes (HBCDDs) in food

in mice can be considered the critical effects. Based on effects on spontaneous behaviour in mice, the Panel identified a lowest observed adverse effect level (LOAEL) of 0.9 mg/kg body weight (bw) as ...

Efficient control of Japanese encephalitis virus in the central nervous system of infected pigs occurs in the absence of a pronounced inflammatory immune response.

Abstract: BACKGROUND: Japanese encephalitis virus (JEV) is the leading cause of viral encephalitis in Asia. JEV infection of mice and humans can lead to an uncontrolled inflammatory response in the central ...

Agglomeration of titanium dioxide nanoparticles increases toxicological responses in vitro and in vivo

vivo, C57BL / 6JR j mice were exposed via oropharyngeal aspiration or oral gavage to TiO2 suspensions and, after 3 days, biological parameters including cytotoxicity, inflammatory cell recruitment, DNA ...

Comments on the “Evaluation of the Genotoxicity of Cell Phone Radiofrequency Radiation in Male and Female Rats and Mice Following Subchronic Exposure” by Smith‐Roe et al.

female rats and mice following subchronic exposure. Smith-Roe SL, Wyde ME, Stout MD, Winters JW, Hobbs CA, Shepard KG, Green AS, Kissling GE, Shockley KR, Tice RR, Bucher JR, Witt KL.Environ Mol Mutagen. ...

Increased surface area of halloysite nanotubes due to surface modification predicts lung inflammation and acute phase response after pulmonary exposure in mice

lung epithelial cells. Lung inflammation, acute phase response and genotoxicity were assessed 1, 3, and 28 days after a single intratracheal instillation of adult female C57BL /6 J BomTac mice. The doses ...

Increased surface area of halloysite nanotubes due to surface modification predicts lung inflammation and acute phase response after pulmonary exposure in mice

Publication Type: Scientific poster, presentation or proceeding Authors: Kenneth Klingenberg Barfod; Katja Maria Bendtsen; Trine Berthing; Antti Joonas Koivisto; Sarah Søs Poulsen; Ester Segal; Eveline Verleysen; Jan Mast; Andreas Holländer; Keld Alstrup ...

Increased surface area of halloysite nanotubes due to surface modification predicts lung inflammation and acute phase response after pulmonary exposure in mice

Publication Type: Scientific poster, presentation or proceeding Authors: Kenneth Klingenberg Barfod; Katja Maria Bendtsen; Trine Berthing; Antti Joonas Koivisto; Sarah Søs Poulsen; Ester Segal; Eveline Verleysen; Jan Mast; Andreas Holländer; Keld Alstrup ...

Inhibition of MALT1 decreases neuroinflammation and pathogenicity of virulent rabies virus in mice.

and a cysteine protease that cleaves substrates, leading to the expression of immunoregulatory genes. Here, we examined the impact of genetic or pharmacological MALT1 inhibition in mice on disease ...

Allergic Asthma Favors Growth in the Lungs of Infected Mice.

bacteria in mice. We observed that i.n. sensitization with extracts of the house dust mite or the mold () significantly increased the number of, and in the lungs of infected mice. Microscopic analysis showed ...

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