Résultats de la recherche - 12 results
Prioritizing substances of genotoxic concern for in-depth safety evaluation using non-animal approaches: The example of food contact materials.
safety. By combining in silico predictions with existing in vitro and in vivo genotoxicity data from publicly available literature sources and results from in vitro gene mutation experiments, the 106 study ...
Assessment of estrogenic compounds in paperboard for dry food packaging with the ERE-CALUX bioassay
a bioanalytical tool to investigate estrogenic activities of paperboard food packaging and its characteristics, including recycling rate and printing ink. A “worst case” scenario with full extraction is compared to ...
A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment
5 known positive and 5 known negative test compounds for genotoxicity was evaluated. In addition, 2 compounds with debatable genotoxicity data were tested to explore how the qPCR array would classify these. ...
Coatings in food contact materials: Potential source of genotoxic contaminants?
harmonized EU regulation exists on chemicals used in coatings for food contact materials (FCM). Therefore, these substances need to comply with the general provisions of EU Regulation 1935/2004 and, if ...
(Q)SAR tools for priority setting: A case study with printed paper and board food contact material substances.
Publication Type: Peer reviewed scientific article Authors: Melissa Van Bossuyt; Els Van Hoeck; Raitano, Giuseppa; Manganelli, Serena; Braeken, Els; Ates, Gamze; Vanhaecke, Tamara; Van Miert, Sabine; Benfenati, Emilio; Mertens, Birgit; Rogiers, Vera Sourc ...
Printed paper and board food contact materials as a potential source of food contamination.
Importantly, 19 substances are also present in one of the lists with substances of concern compiled by the European Chemicals Agency (ECHA). To ensure consumer safety, the actual use of these substances in ...
Evaluation of the potential health risks of substances migrating from polycarbonate replacement baby bottles.
the potential migration risks associated with these alternative materials were investigated. First, all substances were evaluated for endocrine disruptive (ED) activity by using different existing lists ...
. Identification of hazardous compounds used in printed paper and board food contact materials: Pilot study towards the mutagenicity of a selection of compounds with positive in silico results.
Publication Type: Dissertation Authors: Ooghe, N. Source: VUB, Brussels, Belgium, p.50 (2016) Accession Number: NA Keywords: board food contact materials hazardous compounds In silico mutagenicity printed paper Health Topics: Food contact materials Matér ...
Study of the possible migration risks of food contact materials for children under 3 years
concern regarding the possible risks associated with the used alternatives to PC (No. 8697, 11.03.2010). Consequently, alternatives to PC food contact materials (FCM s) for infants, such as polypropylene ...
Evaluation of the migration of chemicals from baby bottles under standardised and duration testing conditions.
microwave, sterilisation and dishwasher, on the migration of different contaminants was evaluated by means of duration tests. These results were compared with a reference treatment (filling five times with ...