Cervical cancer screening program and Human Papillomavirus (HPV) testing, part II: Update on HPV primary screening.

Last updated on 3-10-2023 by Marie Malingreau

Public Access


Peer reviewed scientific article




Key Findings   HPV testing is more sensitive for precancerous lesions CIN2 and CIN3 than cytology. The downside is that the transversal specificity is lower. The protective effect of HPV screening compared to cytology on the incidence of invasive cervical cancer is directly demonstrated in randomized trials. No protective effect is demonstrated under 30 years. The risk of CIN3+ or invasive cervical cancer after a negative hrHPV DNA test is significantly lower than after a negative Pap smear. This means that screening intervals can be extended safely up to five and more. …

Associated health topics:

QR code

QR code for this page URL