Long-term memory response after a single intramuscular rabies booster vaccination, 10-24 years after primary immunization.

Last updated on 12-5-2022 by Steven Van Gucht

Peer reviewed scientific article




BACKGROUND: To date, published data regarding long-lasting immunological rabies memory after a pre-exposure prophylaxis (PrEP)-schedule are scarce. We tested the hypothesis that rabies booster immunization elicits rapid anamnestic responses. METHODS: For this observational study, we included participants who had received PrEP 10-24 years before inclusion. We measured rabies antibody titers before, and on days 3, 7 and 14 after one single intramuscular booster. RESULTS: All 28 participants responded adequately regardless route of administration or (2-dose vs. 3-dose) PrEP-regimen. C…

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