Last updated on 12-12-2024 by Pieter-Jan Ceyssens
Auteurs
Pirnay, Jean-Paul; Djebara, Sarah; Griet Steurs; Griselain, Johann; Cochez, Christel; De Soir, Steven; Glonti, Tea; An Spiessens; Emily Vanden Berghe; Sabrina Green; Wagemans, Jeroen; Lood, Cédric; Eddie Schrevens; Chanishvili, Nina; Kutateladze, Mzia; de Jode, Mathieu; Pieter-Jan Ceyssens; Draye, Jean-Pierre; Verbeken, Gilbert; De Vos, Daniel; Rose, Thomas; Onsea, Jolien; Brieuc Van Nieuwenhuyse; Soentjens, Patrick; Lavigne, Rob; Merabishvili, MayaMots-clés
Résumé:
In contrast to the many reports of successful real-world cases of personalized bacteriophage therapy (BT), randomized controlled trials of non-personalized bacteriophage products have not produced the expected results. Here we present the outcomes of a retrospective observational analysis of the first 100 consecutive cases of personalized BT of difficult-to-treat infections facilitated by a Belgian consortium in 35 hospitals, 29 cities and 12 countries during the period from 1 January 2008 to 30 April 2022. We assessed how often personalized BT produced a positive clinical outcome (general …