Simultaneous determination of parabens, bisphenols and alkylphenols in human placenta by ultra-high performance liquid chromatography - tandem mass spectrometry

Last updated on 30-7-2019 by Ilse Van Overmeire

Peer reviewed scientific article

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SCIENSANO

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Résumé:

This study presents de development and validation of an ultra- high performance liquid chromatography – tandem mass spectrometry (UHPLC-MS/MS) method for the simultaneous determination of four parabens (methyl-, ethyl-, propyl-, and butyl-paraben (MeP, EtP, PrP, BuP), four bisphenols (BP) (BPA, BPB, BPF, and BPS) and two  alkylphenols (nonyl phenol (NP) and tert-octylphenol (OP) in human placenta samples.  After a short sample preparation time the extracts are analysed by UHPLC-MS/MS using negative electrospray ionization.  Labeled internal standards and matrix-matched calibr…

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