Résultats de la recherche - 6 results
Pyrogen testing of phage therapeutic products
contamination (e.g. cell wall debris) is a major safety concern as these pro-inflammatory agents can cause unwanted clinical reactions with potential detrimental outcome. The most common and potent pyrogens are ...
Validation of an animal-free analytical method for the detection of bacterial endotoxins in human vaccines
3R (2023) Keywords: Endotoxin " vaccine " quality control " recombinant factor c " LAL Abstract: Sciensano, as official medicines control laboratory (OMCL) following ...
Determination of vaccine bacterial endotoxins content by the rFC method
factor c; LAL Abstract: Sciensano, as official medicines control laboratory (OMCL) following “Official Control Authority Batch Release” (OCABR) guidelines, is entitled to check the concentration of ...
Homologous versus heterologous prime-boost COVID-19 vaccination: impact on clinical severity of Omicron among hospitalized COVID-19 patients in Belgium
in-hospital mortality, and severe COVID-19 – defined as experiencing an acute respiratory distress syndrome (ARDS) event, or an ICU transfer, or in-hospital mortality) for patients that received a homologous ...
The GEONs API-fingerprint program: Tackling falsifications of APIs
API fingerprint GEON Abstract: Falsification of active pharmaceutical ingredients (API s) has been recognized as an important health issue since a series of health scares involving large numbers of ...
Development of a multiplex immunoassay for simultaneous detection of antigens in DTaP vaccines
development and optimization of the Luminex assay with non-adsorbed antigens and, later, with complete vaccine formulation from HuA and HuB. All selected antibody pairs were tested as capture or detection ...