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Résultats de la recherche - 110 results

Assessing the receptor-mediated activity of PAHs using AhR-, ERα- and PPARγ- CALUX bioassays

s have multiple modes of action and can activate/inhibit multiple receptor signaling pathways known to play critical roles in mediating endocrine disruption. Health Topics:  Health and disease monitoring ...

Assessing the endocrine activity of PAHs using the DRE-, ERE- and PPARγ CALUX bioassays

with our hormonal system by binding to endocrine receptors, resulting in adverse health effects such as reproductive damage, developmental impairment, obesity, diabetes and cancers. The aim of this study ...

Migration of mineral oil from cardboard packaging for food: Identification of the hazards and assessment of the exposure of the Belgian population

to steric hindrance. Furthermore, preliminary results suggest the possible use of bioassays based on activation of the Aryl receptor as a fast screening procedure to detect the presence of MOAH, but ...

Inhibition of MALT1 decreases neuroinflammation and pathogenicity of virulent rabies virus in mice.

protease that mediates the activation of several innate and adaptive immune cells in response to multiple receptors, and therapeutic MALT1 targeting is believed to be a valid approach for autoimmunity and ...

Multivalent binding of herpesvirus to living cells is tightly regulated during infection.

8 (2018) Abstract: Viral infection, initiated by the landing of a virion on a cellular surface, is largely defined by the preliminary interactions established between viral particles and their receptors at ...

Activity-Based Detection and Bioanalytical Confirmation of a Fatal Carfentanil Intoxication.

a fatality in Norway. Blood, urine and vitreous, obtained during autopsy, were screened with a newly developed opioid activity reporter assay able to detect compounds based on their μ-opioid receptor activity ...

Inflammatory Properties and Adjuvant Potential of Synthetic Glycolipids Homologous to Mycolate Esters of the Cell Wall of Mycobacterium tuberculosis.

health Public-health Receptor response Responses result results Service Species strain structure study sugar Synthetic System TDM Term Tuberculosis vaccine vaccines WIV-ISP Abstract: The cell wall of ...

Innate signaling by mycolate esters of the cell wall of Mycobacterium tuberculosis and relevance for development of adjuvants for subunit vaccines

Rather, the nature of the sugar and the number of acyl chains bound to it seem to dictate the affinity of the glycolipid for Mincle receptor in vitro. In vivo, we observed that TDM, TMM and GMM induce ...

PKC epsilon-dependent calcium oscillations associated with metabotropic glutamate receptor 5 prevent agonist-mediated receptor desensitization in astrocytes.

Kinase C-epsilon rats Rats, Sprague-Dawley Receptor, Metabotropic Glutamate 5 Transduction, Genetic Abstract: A critical role has been assigned to protein kinase C (PKC)ε in the control of intracellular ...

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