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Zoekresultaten - 21 results
Assessment of receptor-mediated activity (AhR and ERα), mutagenicity, and teratogenicity of metal shredder wastes in Wallonia, Belgium.
the bacterial reverse gene mutation test using the Salmonella typhimurium TA98 and TA100 strains. Except for the sludge sample (site 3), all samples induced a mutagenic response in the TA98 strain (± ...
In Silico Methods for Chromosome Damage.
Keywords: Chromosome Aberrations Chromosomes DNA Damage Humans Mutagenicity Tests Mutagens Mutation Abstract: Due to the link with serious adverse health effects, genotoxicity is an important toxicological ...
In silico methods for chromosome damage
induction of structural or numerical chromosome aberrations, several in vitro and in vivo test methods are available. In order to rapidly collect toxicological data without the need for test material, several ...
Identification of flavouring substances of genotoxic concern present in e-cigarette refills
Vera; Eric Deconinck; Vanhaecke, Tamara Source: Food and Chemical Toxicology, Volume 147, Issue 111864 (2021) Keywords: (Q)SAR methodologies e-cigarettes genotoxicity mutagenicity Abstract: E-cigarettes ...
A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment
Keersmaecker; Rogiers, Vera; Tatyana Y. Doktorova Source: Archives of Toxicology (2018) Keywords: genotoxicity HepaRG In vitro screening mutagenicity qPCR array Toxicogenomics Abstract: Although the value of the ...
Coatings in food contact materials: Potential source of genotoxic contaminants?
Toxicol, Volume 106, Issue Pt A, Number 505, p.496-505 (2017) Keywords: Consumer Product Safety Food Contamination Food Packaging Humans Mutagenicity Tests Mutagens Abstract: Up till now, no harmonized EU ...
(Q)SAR tools for priority setting: A case study with printed paper and board food contact material substances.
Sabine; Benfenati, Emilio; Mertens, Birgit; Rogiers, Vera Source: Food Chem Toxicol, Volume 102, Number 119, p.109-119 (2017) Keywords: Computer Simulation Food Packaging Mutagenicity Tests Organic ...
The correlation between antimutagenic activity and total phenolic content of extracts of 31 plant species with high antioxidant activity.
Altern Med, Volume 16, Issue 1, Number 13, p.490 (2016) Keywords: Antimutagenic Agents Antioxidants Mutagenicity Tests Phenols Plant Extracts Plant Leaves Plants Salmonella typhimurium Abstract: ...
In silico tools and transcriptomics analyses in the mutagenicity assessment of cosmetic ingredients: a proof-of-principle on how to add weight to the evidence.
Alessandra; Milushev, Dimiter; Benfenati, Emilio; Rogiers, Vera; Doktorova, Tatyana Y Source: Mutagenesis, Volume 31, Number 461, p.453-61 (2016) Keywords: Cosmetics In silico Mutagenicity Tests Transcriptomics ...
Linking existing in vitro dermal absorption data to physicochemical properties: Contribution to the design of a weight-of-evidence approach for the safety evaluation of cosmetic ingredients with low dermal bioavailability.
No-Observed-Adverse-Effect Level Risk Assessment SKIN Skin Absorption Structure-Activity Relationship Toxicity Tests Abstract: To characterize the risk of cosmetic ingredients when threshold toxicity is assumed, often the ...