
Zoekresultaten - 63 results
A decalogue of Molecular Tumor Board (MTB) recommendations from the CAN.HEAL Consortium
across 17 EU countries, has developed a set of recommendations for Molecular Tumor Boards (MTB s) to address the lack of standardized guidelines in personalized cancer medicine. Health Topics: Cancer ...
Development and implementation of novel liquid biopsy NGS panels via the OncNGS precommercial procurement (PCP) initiative
Volume 10, Issue 6 (2025) Keywords: comprehensive genomic profiling (CGP) ctDNA liquid biopsy OncNGS precommercial procurement (PCP) Abstract: Background Circulating tumor DNA (ctDNA) analysis is ...
EU Oncology Decision Support Tool concept (CAN.HEAL Deliverable 10.1)
and interoperability of oncDSTs to support the management of oncological processes and drive further advancements in the field. The framework aims to support Molecular Tumor Board (MTB) operations ...
Sphaeropsidin A C15-C16 Cross-Metathesis Analogues with Potent Anticancer Activity.
A L; Mathieu, Véronique; Kornienko, Alexander Source: ChemMedChem, Volume 19, Issue 18 (2024) Keywords: Antineoplastic Agents Ascomycota Cell Line, Tumor Cell Proliferation Dose-Response Relationship, ...
PRECISION: the Belgian molecular profiling program of metastatic cancer for clinical decision and treatment assignment.
tumors molecularly guided treatments. The PRECISION 1 study has led to the creation of a clinico-genomic database. The Belgian Approach for Local Laboratory Extensive Tumor Testing (BALLETT) and GeNeo ...
Reduced humoral immune response after BNT162b2 coronavirus disease 2019 messenger RNA vaccination in cancer patients under antineoplastic treatment.
PATIENTS AND METHODS: In this interventional prospective multicohort study, priming and booster doses of the BNT162 b2 COVID-19 vaccine were administered 21 days apart to solid tumor patients receiving ...
Lentiviral vector induces high-quality memory T cells via dendritic cells transduction.
lentiviral vector provided enhance therapeutic anti-tumor protection than Ad5. In conclusion, coupling lentiviral vector with β2-microglobulin promoter represents a promising approach to produce long-lasting, ...
Progressive Control of Streptococcus agalactiae-Induced Innate Inflammatory Response Is Associated with Time Course Expression of MicroRNA-223 by Neutrophils.
Tumor Necrosis Factor-alpha Abstract: Group B streptococcus (GBS) is a human-pathogenic bacterium inducing a strong inflammatory response that may be detrimental for host tissues if not finely regulated. ...
NGS for (Hemato-) Oncology in Belgium: Evaluation of Laboratory Performance and Feasibility of a National External Quality Assessment Program
in Belgium. DNA samples derived from cell line mixes and artificially mutated cell lines, designed to carry variants of clinical relevance occurring in solid tumors, hematological malignancies, and ...
Association of Endometrial Cancer Risk With Postmenopausal Bleeding in Women: A Systematic Review and Meta-analysis.
irrespective of tumor stage. The pooled risk of endometrial cancer among women with PMB was 9% (95% CI, 8%-11%), with estimates varying by use of hormone therapy (range, 7% [95% CI, 6%-9%] to 12% [95% CI, ...