Zoekresultaten - 204 results
Pre-registration efficacy study of a novel marker vaccine against classical swine fever on Maternally Derived Antibody negative (MDA-) target animals.
prepared in cell cultures), classical” 7th Edition, which claims the efficacy test is invalid if fewer than 50 per cent of the control piglets display typical signs of serious infection of CSF or die, and if ...
CCR2(+)CD103(-) intestinal dendritic cells develop from DC-committed precursors and induce interleukin-17 production by T cells.
Interferon Regulatory Factors Interleukin-12 Interleukin-17 Intestinal Mucosa Macrophages mice Mice, Transgenic Monocytes Phagocytes Phenotype Receptors, CCR2 T-Lymphocyte Subsets Th17 Cells Abstract: The ...
The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family.
aethiops Enterovirus B, Human HeLa Cells Humans Poliovirus RNA-Dependent RNA Polymerase Viral Proteins Abstract: The genus Enterovirus of the family Picornaviridae contains many important human pathogens ...
A thiazepino[4,5-a]benzimidazole derivative hampers the RNA replication of Eurasian serotypes of foot-and-mouth disease virus.
King, Donald P; Neyts, Johan; Kris De Clercq Source: Biochem Biophys Res Commun, Volume 455, Issue 3-4, p.378-81 (2014) Keywords: Animals Antiviral Agents Benzimidazoles Cell Line Cell Survival ...
The combination of attenuated Newcastle disease (ND) vaccine with rHVT-ND vaccine at 1 day old is more protective against ND virus challenge than when combined with inactivated ND vaccine.
Keywords: Animals Chickens Enzyme-Linked Immunosorbent Assay Herpesvirus 1, Meleagrid Newcastle Disease Newcastle disease virus Poultry Diseases Statistics, Nonparametric Th1 Cells Vaccines, Attenuated ...
Vaccination of mice using the West Nile virus E-protein in a DNA prime-protein boost strategy stimulates cell-mediated immunity and protects mice against a lethal challenge.
Immunity, Cellular Immunization Immunization, Secondary mice Nanoparticles Th2 Cells Vaccines, DNA Viral Envelope Proteins West Nile Fever West Nile virus West Nile Virus Vaccines Abstract: West Nile virus ...
Analysis of the vaccine potential of plasmid DNA encoding nine mycolactone polyketide synthase domains in Mycobacterium ulcerans infected mice.
encoding Ag85A or with M. bovis BCG. Strongest antigen specific antibodies could be detected in response to acyltransferase (propionate) and enoylreductase. Antigen-specific Th1 type cytokine responses (IL-2 ...
Substituted 2,6-bis(benzimidazol-2-yl)pyridines: a novel chemical class of pestivirus inhibitors that targets a hot spot for inhibition of pestivirus replication in the RNA-dependent RNA polymerase.
Neyts, Johan; Paeshuyse, Jan Source: Antiviral Res, Volume 106, p.71-9 (2014) Keywords: Animals Antiviral Agents Benzimidazoles Cattle Cell Line Classical swine fever virus Diarrhea Virus 1, Bovine Viral ...
In vitro surrogate models to aid in the development of antivirals for the containment of foot-and-mouth disease outbreaks.
Johan; Goris, Nesya Source: Antiviral Res, Volume 105, p.59-63 (2014) Keywords: Animals Antiviral Agents Aphthovirus Benzimidazoles Cattle Cell Line Chlorocebus aethiops Cytidine Cytopathogenic Effect, ...
Cytokine and immunoglobulin isotype profiles during CP7_E2alf vaccination against a challenge with the highly virulent Koslov strain of classical swine fever virus.
vaccine and challenge strain. Interestingly, IFN-γ enhancement and persistent high IgG2 levels suggested an important role of cell-mediated immunity in long-term protection against CSFV induced by CP7_E2alf ...