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Zoekresultaten - 21 results
Immunogenicity and protective efficacy of tuberculosis subunit vaccines expressing PPE44 (Rv2770c).
Publication Type: Peer reviewed scientific article Authors: Marta Romano; Rindi, Laura; Korf, Hannelie; Bonanni, Daniela; Adnet, Pierre-Yves; Fabienne Jurion; Garzelli, Carlo; Huygen, Kris Source: Vaccine, Volume 26, Issue 48, p.6053-63 (2008) Keywords: A ...
Antagonist-radioligand binding to D2L-receptors in intact cells.
Here we compared [(3)H]-raclopride and [(3)H]-spiperone binding properties in intact Chinese Hamster Ovary cells stably expressing recombinant human D(2L)-receptors. Specific binding of both radioligands ...
99mTc-Labeled Nanobodies: A New Type of Targeted Probes for Imaging Antigen Expression
Publication Type: Peer reviewed scientific article Authors: Cortez-Retamozo, Virna; Lahoutte, Tony; V Caveliers; Tchouate Gainkam, Lea; Hernot, Sophie; Ann Packeu; F De Vos; Vanhove, Chris; Muyldermans, Serge; P De Baetselier; Revets, Hilde Source: Curren ...
The caspase-generated fragments of PKR cooperate to activate full-length PKR and inhibit translation.
fragments could independently co-precipitate with full-length PKR. Expression of PKR- KD leads to PKR and eIF2-alpha phosphorylation and inhibits protein translation, whereas that of PKR- ND does not. ...
Immunogenicity of eight dormancy regulon-encoded proteins of Mycobacterium tuberculosis in DNA-vaccinated and tuberculosis-infected mice.
Tuberculosis Tuberculosis Vaccines Vaccines, DNA Abstract: Hypoxia and low concentrations of nitric oxide have been reported to upregulate in vitro gene expression of 48 proteins of the dormancy (DosR) regulon ...
Immunogenicity and protective efficacy of tuberculosis DNA vaccines combining mycolyl-transferase Ag85A and phosphate transport receptor PstS-3.
tuberculosis in C57BL /6 mice. Here we have analysed the vaccine potential of a combination of both antigens using plasmid vectors expressing either a fusion protein of both antigens or the separate proteins ...
Evaluation of the immunogenicity of pBudCE4.1 plasmids encoding mycolyl-transferase Ag85A and phosphate transport receptor PstS-3 from Mycobacterium tuberculosis.
mice challenged with Mtb. In order to combine the protection against Mtb infection induced by these two DNA vaccines, we have cloned Ag85A and PstS-3 in pBudCE4.1 vector, in which antigenic expression is ...
Distinct VH repertoires in primary and secondary B cell lymphocyte subsets in the preimmune repertoire of A/J mice: the CRI-A idiotype is preferentially associated with the HSA(low) B cell subset.
The anti-arsonate immune response of A/J mice is characterized by the occurrence of several recurrent idiotypes with a different temporal pattern of expression. The CRI-A idiotype is typically a memory ...
Immunogenicity and protective efficacy of DNA vaccines encoding secreted and non-secreted forms of Mycobacterium tuberculosis Ag85A.
types of Ag85A- DNA vaccines; those expressing secreted and non-secreted forms of the protein. DESIGN: Ag85A- DNA vaccinated mice were challenged with a highly virulent clinical isolate of M. tuberculosis ...
Metabolic reprogramming of Pseudomonas aeruginosa by phage-based quorum sensing modulation.
density-dependent signaling system by expressing quorum sensing targeting protein (Qst) early during infection. We demonstrate that Qst interacts with PqsD, a key host quinolone signal biosynthesis pathway enzyme, ...