Zoekresultaten - 45 results
Cardiovascular risk factors and complications associated with albuminuria and impaired renal function in insulin-treated diabetes.
of albuminuria and reduced eGFR was associated with the worst cardiovascular outcomes. CONCLUSIONS: Albuminuria and impaired renal function are prevalent in type 1 and insulin-treated type 2 diabetes. ...
Optimising the case-crossover design for use in shared exposure settings.
bias. In contrast to systematic bias, confounding bias can be hard to detect. We studied potential solutions: varying the model parameters and link-function, outlier-removal and aggregating the input-data ...
Metabolic reprogramming of Pseudomonas aeruginosa by phage-based quorum sensing modulation.
resulting in decreased levels of PQS and its precursor 2-heptyl-4(1H)-quinolone. The lack of a functional PqsD enzyme impairs LUZ19 infection but is restored by external supplementation of ...
The Phage-Encoded-Acetyltransferase Rac Mediates Inactivation of Transcription by Cleavage of the RNA Polymerase Alpha Subunit.
study, we describe the biological function of the phage-encoded protein RNA polymerase alpha subunit cleavage protein (Rac), a predicted Gcn5-related acetyltransferase encoded by phiKMV-like viruses. These ...
Transcriptional profiling of a laboratory and clinical Mycobacterium tuberculosis strain suggests respiratory poisoning upon exposure to delamanid.
delamanid. Remarkably, the most highly induced genes comprise poorly characterized genes for which functional characterization might hint to the target molecule(s) of delamanid and its exact mode(s) of action. ...