Zoekresultaten - 34 results
Linking existing in vitro dermal absorption data to physicochemical properties: Contribution to the design of a weight-of-evidence approach for the safety evaluation of cosmetic ingredients with low dermal bioavailability.
not be an issue. This study shows the possibility of identifying compounds suspected to have a low dermal bioavailability based on their physicochemical properties (molecular weight, melting point, ...
Analysis of illegal peptide biopharmaceuticals frequently encountered by controlling agencies.
technologies and peptide synthesis have led to an increased development of protein and peptide therapeutics. Unfortunately this goes hand in hand with a growing market of counterfeit and illegal ...
In vitro Dermal Absorption: Sample Application and Seal Quality in a Franz Diffusion Cell System.
Consumer Safety (SCCS) have published guidance documents of how to perform these in vitro tests. For the parameter ‘sample application’ and ‘adequate seal’, it is indicated to apply the sample homogeneously ...
Accuracy of linear measurements using three imaging modalities: two lateral cephalograms and one 3D model from CBCT data.
inter-observer agreement based on 3D measurements was slightly better than others. LIMITATIONS: Dry human skulls without soft tissues were used. Therefore, the results have to be interpreted with caution, as they ...
HS-GC-MS method for the analysis of fragrance allergens in complex cosmetic matrices.
Cosmetic Regulation with labelling and concentration restrictions. This means that they have to be declared on the ingredients list, when their concentration exceeds the labelling limit of 10 ppm or 100 ppm ...
General considerations on the biosafety of virus-derived vectors used in gene therapy and vaccination.
Publication Type: Peer reviewed scientific article Authors: Aline Baldo; van den Akker, Eric; Bergmans, Hans E; Lim, Filip; Katia Pauwels Source: Curr Gene Ther, Volume 13, Issue 6, Number 394, ...
Chromatography in the detection and characterization of illegal pharmaceutical preparations.
for analytical laboratories to detect and characterize them. Spectroscopic techniques such as infrared spectroscopy and Raman spectroscopy have always been the first methods of choice to detect ...
Development and validation of a fast chromatographic method for screening and quantification of legal and illegal skin whitening agents.
latter having restrictions with respect to concentration and application (kojic acid, arbutin, nicotinamide and salicylic acid), but can also quantify these in a run time of 12 min. The method was ...
Classification trees based on infrared spectroscopic data to discriminate between genuine and counterfeit medicines
and counterfeit medecines. One thing all these techniques have in common is that they generate a huge amount of data, which is often difficult to interpret in order to see differences between the ...
Accuracy and reproducibility of automated estradiol-17beta and progesterone assays using native serum samples: results obtained in the Belgian external assessment scheme.
ranging from-8% to 32% for E(2) and from 7% to 41% for progesterone. CONCLUSIONS: Few automated methods succeed in having an excellent reproducibility for E(2) and progesterone. Given the high bias values ...