An appetite for destruction: from self-eating to cell cannibalism as a neuronal survival strategy4382

Last updated on 22-8-2019 by Anonymous (niet gecontroleerd)

Public Access

Published

Peer reviewed scientific article

Samenvatting:

Autophagy plays an important role in cellular survival by resupplying cells with nutrients during starvation or by clearing misfolded proteins and damaged organelles and thereby preventing degenerative diseases. Conversely, the autophagic process is also recognized as a cellular death mechanism. The circumstances that determine whether autophagy has a beneficial or a detrimental role in cellular survival are currently unclear. We recently showed that autophagy induction is detrimental in neurons that lack a functional AMPK enzyme (AMP-activated protein kinase) and that suffer from severe me…

Associated health topics:

QR code

QR code for this page URL