Characterization of suspected dermal fillers containing hyaluronic acid

Last updated on 22-8-2019 by Anonymous (niet gecontroleerd)

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Peer reviewed scientific article



Hyaluronic acid (HA) has important applications in the field of orthopedics, ophthalmology and cosmetics. This polymer can be present in cosmetic products or can be used as a dermal filler. The latter frequently contains cross-linked HA. Today's methods to quantify the amount of cross-linked HA are not very specific. In this paper the development and validation of a specific identification and quantification method is described. The proposed method utilizes an essential pre-extraction step prior to identification by infra-red spectroscopy followed by an identity confirmation and quantif…

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