Contained use of bacteriophages: Risk assessment and biosafety recommendations

Last updated on 22-8-2019 by Anonymous (niet gecontroleerd)

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Non-peer reviewed scientific publication



Bacteriophages are bacterial viruses and consist ofa single- or double-stranded DNA or RNA protected bya protein capsid. They are able to infect bacteria byinjecting their nucleic acids inside the host. The virusesmultiply and induce lysis of the host cell, or they arestabilized as prophage, either inserted in the bacterialgenome or as independent plasmid molecules. Bacteriophagesrepresent the most numerous micro-organismsfound on earth and play a major role in bacterial evolutionby serving as a genomic reservoir in the environmentand by promoting lateral gene transfer amongbacteria through…

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