Critical aspects in implementing the OECD monograph No. 14 "the application of the principles of GLP to in vitro studies".

Last updated on 22-8-2019 by Anonymous (niet gecontroleerd)

Peer reviewed scientific article



The Organisation for Economic Cooperation and Development (OEC D) principles of good laboratory practice (GLP) were originally developed for application to animal-based toxicology studies. On the other hand, more and more studies involving in vitro test systems are performed to produce data on the safety of chemicals with respect to human health and the environment. Therefore, national legislation usually requires that the in vitro studies are conducted in compliance with the GLP principles. Furthermore, developments in the area of toxicogenomics, toxicoproteomics, toxicometabonomics and va…

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