Last updated on 19-8-2024 by Stéphanie Depickère
Public Access
Published
Auteurs
Nicolas Gemander; Delphine Kemlin; Stéphanie Depickère; Natasha S. Kelkar; Pieter Pannus; Shilpee Sharma; Alexandra Waegemans; Véronique Olislagers; Daphnée Georges; Emilie Dhondt; Margarida Braga; Leo Heyndrickx; Johan Michiels; Anaïs Thiriard; Anne Lemy; Marylène Vandevenne; Maria Goossens; André Matagne; I sabelle Desombere; Kevin K. Ariën; Margaret E. Ackerman; Alain Le Moine; Arnaud MarchantTrefwoorden
Samenvatting:
Introduction
Comorbidities and immunosuppressive therapies are associated with reduced immune responses to primary COVID-19 mRNA vaccination in kidney transplant recipients (KTRs). In healthy individuals, prior SARS-COV-2 infection is associated with increased vaccine responses, a phenotype called hybrid immunity. In this study, we explored the potential influence of immune suppression on hybrid immunity in KTRs.
Methods
Eighty-two KTRs, including 59 SARS-CoV-2-naïve (naïve KTRs [N-KTRs]) and 23 SARS-CoV-2-experienced (experienced KTRs [E-KTRs]) patients, were prospectively studied and c…