Pivotal role of ChIFNgamma in the pathogenesis and immunosuppression of infectious bursal disease.

Last updated on 23-8-2019 by Anonymous (niet gecontroleerd)

Peer reviewed scientific article

SCIENSANO

Samenvatting:

This study investigates the pivotal role of chicken interferon-gamma (ChIFNgamma) in the pathogenesis and immunosuppression of infectious bursal disease virus (IBDV) infection and is divided into in vivo, ex vivo and in vitro experiments. Two-week-old specific pathogen free chickens were inoculated with the 849VB very virulent strain of IBDV. The levels of systemic ChIFNgamma and chicken interleukin-6 in the serum were followed for 2 weeks during in vivo experiments. Then, splenocytes and bursal cells from infected chickens were analysed for their immunocompetence after mitogenic activation…

Associated health topics:

QR code

QR code for this page URL