Salmonella enterica serovar Enteritidis colonization of the chicken caecum requires the HilA regulatory protein36756

Last updated on 23-8-2019 by Anonymous (niet gecontroleerd)

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Peer reviewed scientific article


Invasion of Salmonella into intestinal epithelial cells is believed to be essential for the pathogenesis of Salmonella infections. Invasion is mediated by genes located on the Salmonella pathogenicity Island I (SPI-1), which are needed for assembling a type three secretion system, that mediates injection of bacterial proteins into the cytosol of epithelial cells, resulting in cytoskeletal rearrangements and as a consequence invasion. HilA is the key regulator of the Salmonella Pathogenicity Island I. To assess the role of hilA in colonization of gut and internal organs in poultry, animals w…

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