Very Long Persistence of Botulinum Toxin B in a Patient’s Serum

Background:

Botulinum toxins (BoNT) type A, B, E, F may induce a serious neuroparalytic illness in humans. Botulism can be transmitted via

three routes: foodborne, wound and intestinal (in situ toxemia generally observed in infants and/or in immunocompromised adults)

botulism.

Case Report:

A case of human botulism type B due to the consumption of an imported dried ham is reported. Laboratory results confirmed the

diagnosis using the mouse bioassay and the qPCR method. Botulinum toxin was still detected in the serum up to 29 days after food

consumption while it was not detected anymore in the faeces.

Conclusion:

The described case highlights i) prolonged presence of BoNT B in the serum and ii) the risks related to the preparation of artisanal

products as well as the importance of an efficient communication to citizens regarding preservation methods of household products.