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Discovery and Development of an Advanced Lead for the Treatment of African Trypanosomiasis.

Caljon, Guy Source: ACS Infect Dis, Volume 11, Issue 1 (2025) Keywords: Animals Disease Models, Animal Drug Discovery Drug Evaluation, Preclinical Humans mice Nucleosides Trypanocidal Agents Trypanosoma ...

Assessment of Innovative Dry Powders for Inhalation of a Synergistic Combination Against Mycobacterium tuberculosis in Infected Macrophages and Mice

Publication Type: Peer reviewed scientific article Authors: Ravon, Faustine; Berns, Emilie; Lambert, Isaline; Rens, Céline; Adnet, Pierre-Yves; Kiass, Mehdi; Megalizzi, Véronique; Delporte, Cedric; Baulard, Alain; Vanessa Mathys; Samira Boarbi; Wauthoz, N ...

Assessment of receptor-mediated activity (AhR and ERα), mutagenicity, and teratogenicity of metal shredder wastes in Wallonia, Belgium.

GTP-Binding Proteins Hazardous Waste Industrial Waste Metals mice mutagenesis Receptors, Aryl Hydrocarbon RNA-Binding Proteins Salmonella typhimurium Zebrafish Abstract: In this study, hazardous wastes ...

The future burden of type 2 diabetes in Belgium: a microsimulation model.

Chained Equations (MICE) as inputs to the Simulation of Synthetic Complex Data (simPop) model. Mortality information was obtained from the Belgian vital statistics and used to calculate annual death ...

Replacement of Diphtheria and Tetanus potency challenge method by serology in mice

Publication Type: Scientific poster, presentation or proceeding Authors: J. Auquier Source: Annual OMCL Meeting 2023, EDQM, Madrid (2023) Keywords: 3R Diphtheria serology Tetanus vaccine Health Topics:  Vaccin Vaccin Vaccin Service:  Qualité des vaccins e ...

In vitro and in vivo local tolerability of a synergistic anti-tuberculosis drug combination intended for pulmonary delivery.

Nathalie Source: J Appl Toxicol, Volume 43, Issue 2 (2023) Keywords: Alveolar Epithelial Cells Animals Antitubercular Agents Bronchoalveolar Lavage Fluid Humans Lung mice Mycobacterium tuberculosis Orlistat ...

Sex difference in innate inflammatory response and macrophage polarization in Streptococcus agalactiae-induced pneumonia and potential role of microRNA-223-3p.

1 (2022) Keywords: Animals Antagomirs Cytokines Female Inflammation Macrophages Male mice MicroRNAs Pneumonia Sex Characteristics Streptococcus agalactiae Abstract: While number of studies have shown that ...

Pharmacokinetics of Oral Rebaudioside A in Patients with Type 2 Diabetes Mellitus and Its Effects on Glucose Homeostasis: A Placebo-Controlled Crossover Trial

observed for rebaudioside A in mice, they have been attributed to the metabolites steviol and steviol glucuronide. We aimed to characterize the pharmacokinetic and pharmacodynamic properties of rebaudioside ...

A Role for B Cells to Transmit Hepatitis C Virus Infection.

B-Lymphocytes Broadly Neutralizing Antibodies Disease Models, Animal Female Hepacivirus Hepatitis C Humans Liver Liver Transplantation Male mice middle aged serum Transplantation Chimera Vaccine Development Viral ...

Lentiviral vector induces high-quality memory T cells via dendritic cells transduction.

Lentivirus mice Mice, Inbred C57BL Promoter Regions, Genetic Transduction, Genetic Transgenes Abstract: We report a lentiviral vector harboring the human β2-microglobulin promoter, with predominant expression ...

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