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Zoekresultaten - 42 results
Physicochemical characterization and genotoxicity assessment of nanomaterials using new approach methodologies
containing a fraction of nanoparticles [4], as well as new innovative NAM s such as the transcriptomics-based biomarker, called GENOMARK. This NAM uses prediction models to classify analyzed materials as ...
Lifestyle predictors of colorectal cancer in European populations: a systematic review
Issue 1 (2024) Abstract: BACKGROUND: Colorectal cancer (CRC) is the second most prevalent cancer in Europe, with one-fifth of cases attributable to unhealthy lifestyles. Risk prediction models for ...
Unlocking the Power of Transcriptomic Biomarkers in Qualitative and Quantitative Genotoxicity Assessment of Chemicals.
generated using the TempO-Seq technology. We found a prediction performance of 100%, confirming the applicability of GENOMARK to TempO-Seq. Classification using TG x- DDI was then compared to GENOMARK. For ...
VERMEER FCM: A tool integrating exposure and hazard modelling for chemicals migrating from food contact materials
Hoeck; Birgit Mertens Source: Food and Chemical Toxicology, Volume 193 (2024) Keywords: food contact materials Hazard prediction In silico Migration Modelling VEGA Abstract: A new tool, VERMEER FCM, was ...
Full Characterisation of Heroin Samples Using Infrared Spectroscopy and Multivariate Calibration
Squares (PLS) modelling, in order to obtain qualitative and quantitative models based on real live samples. The approach showed that it was possible to identify and quantify heroin in the samples based on ...
Multidimensional chromatographic fingerprinting combined with chemometrics for the identification of regulated plants in suspicious plant food supplements
explored: (a) binary modelling and (b) multiclass modelling. The correct classification rate % (ccr%) for cross validation, modelling and external test prediction were used to select the optimal model for ...
SCORE2-Diabetes: 10-year cardiovascular risk estimation in type 2 diabetes in Europe.
develop and validate a recalibrated prediction model (SCORE2-Diabetes) to estimate the 10-year risk of cardiovascular disease (CVD) in individuals with type 2 diabetes in Europe. METHODS AND RESULTS: ...
Time series modelling for wastewater-based epidemiology of COVID-19: A nationwide study in 40 wastewater treatment plants of Belgium, February 2021 to June 2022
metrics at different lag times were used to predict incident COVID-19 cases. Model selection was based on AIC c minimization. Results: In 3¾0 WWTP s, RNA levels were best explained by incident cases, flow ...
Novel prediction models for genotoxicity based on biomarker genes in human HepaRG™ cells.
DNA microarray profiles of 24 (non-)genotoxic reference chemicals covering different modes of action in metabolically competent human HepaRG™ cells. In the present study, new prediction models for ...
Novel prediction models for genotoxicity based on biomarker genes in human HepaRGTM cells
microarray profiles of 24 (non-)genotoxic reference chemicals covering different modes of action in metabolically competent human HepaRG™ cells. In the present study, new prediction models for genotoxicity ...