A simple dilute and shoot methodology for the identification and quantification of illegal insulin

Last updated on 22-8-2019 by Anonymous (niet gecontroleerd)

Peer reviewed scientific article

Engels

Samenvatting:

The occurrence of illegal medicines is a well-established global problem and concerns mostly small molecules. However, due to the advances in genomics and recombinant expression technologies there is an increased development of polypeptide therapeutics. Insulin is one of the best known polypeptide drug, and illegal versions of this medicine led to lethal incidents in the past. Therefore, it is crucial for the public health sector to develop reliable, efficient, cheap, unbiased and easily applicable active pharmaceutical ingredient (API) identification and quantification strategies for routi…

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