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Zoekresultaten - 5 results
Controlled Human Infection Studies: Proposals for guidance on how to design, develop and produce a challenge strain.
Pieter Source: Biologicals, Volume 74 (2021) Abstract: There is an increasing need to establish quality principles for designing, developing and manufacturing challenge agents as currently these agents are ...
The Importance of Quality Control of LSDV Live Attenuated Vaccines for Its Safe Application in the Field.
(GTPV), in addition to vaccine LSDV. New phylogenetic PCR s were developed to characterize in detail the genomic content and a vaccination/challenge trial was conducted to evaluate the impact on efficacy ...
Comparative Evaluation of Lumpy Skin Disease Virus-Based Live Attenuated Vaccines.
purpose of this study to compare five homologous live attenuated LSDV vaccines (LSDV LAV) in a standardized setting. All five LSDV LAV s studied were able to protect against a challenge with virulent LSDV. ...
Human challenge trial workshop: Focus on quality requirements for challenge agents, Langen, Germany, October 22, 2019.
responses as a basis for the development of vaccines. In controlled human infection models, human challenge agents are used to infect healthy volunteers, therefore, ethical considerations include that the ...
Phage Biobank: Present Challenges and Future Perspectives.
improve the reproducibility, safety and speed of the provision of suitable phages. Here we discuss the specific characteristics and challenges of a sustainable phage biobank and, as we build a national ...