Zoekresultaten - 8 results
A Transcriptomic Biomarker to Classify Chemical-Induced Histone Deacetylase Inhibition in Human HepaRGTM Cells
Science Forum, Ottawa, Canada (2024) Keywords: HepaRG cells histone deacetylase inhibition transcriptomic biomarker Health Topics: Health and environment Santé et environnement Gezondheid en milieu ...
The GENOMARK transcriptomic biomarker demonstrates a high predictivity for genotoxic hazards and utility in potency ranking in human HepaRGTM cells
Publication Type: Scientific poster, presentation or proceeding Authors: Anouck Thienpont; Eunnara Cho; Andrew Williams; Matthew Meier; Carole Yauk; Vera Rogiers; Tamara Vanhaecke; Birgit Mertens Source: EEMGS meeting, Malaga, Spain (2023) Keywords: bench ...
The GENOMARK biomarker inhuman HepaRGTM cells: a new approach methodology for genotoxicity assessment
Publication Type: Scientific poster, presentation or proceeding Authors: Anouck Thienpont; Stefaan Verhulst; Leo van Grunsven; Vera Rogiers; Tamara Vanhaecke; Birgit Mertens Source: SaferWorldByDesign webinar, Online (2023) Keywords: genotoxicity NAM tran ...
Biological activity conferred by endocrine disrupting chemicals in hospital effluent and river water from the Brussels Region, Belgium
gene expression) bioassay using a luciferase reporter gene as part of BG1 luc4E2 cells (human ovarian adenocarcinoma). Responses are time, dose, and ligand specific using 17β-estradiol (the natural ...
In vitro model to study the endocrine disrupting activity of migration products from plastic food contact materials
(these) activity(ies) will be explored using cell based transactivational assays also named “reporter gene assays. The MCF7 recombinant cells used here are genitically modified cells containing the firefly ...
Genotoxicity of water extracts from hypoxis species
and H. acuminata and from a commercial preparation thereof using the neutral red uptake (NRU) assay, the alkaline comet assay and the cytome assay in human hepatoma HepG2 cells. The relative ...
Cytome assay in two cell lines exposed to ELF-magnetic fields: An investigation on the relation between exposure to ELF-magnetic fields and an alleged increased risk for Alzheimer's disease.
Issue UNIVERSITY OF MALTA, La Valetta, Malta (2012) Keywords: Alzheimer C3A cytome assay ELF magnetic fields micronucleus nuclear bud SH-SY5Y Abstract: Cell division disturbances, including trisomy ...
Combretum microphyllum and Leucospermum erubescens inhibit the genotoxic effects of 4-NQO, MMC and EMS in vitro
Pharmacology (ACP2012), University of Pretoria- Dept. of Pharmacology, Issue Dept.Pharmacology,Univertsity of Pretoria, Pretoria (2012) Keywords: Activity Africa ALL an AS Belgium Brussels cancer cells Clinical ...