Zoekresultaten - 7 results
Pyrogen testing of phage therapeutic products
these last years, with treatments provided to more than 100 patients, against more than 10 different bacterial species. Therapeutic phage products are produced in a bacterial host strain, hence pyrogen ...
Validation of an animal-free analytical method for the detection of bacterial endotoxins in human vaccines
“Official Control Authority Batch Release” (OCABR) guidelines, is entitled to check the concentration of endotoxin in bacterial vaccines. The limulus amebocyte lysate (LAL) and the recombinant factor C (rFC) ...
Determination of vaccine bacterial endotoxins content by the rFC method
endotoxin in bacterial vaccines. The limulus amebocyte lysate (LAL) and the recombinant factor C (rFC) assays are suitable for all vaccines tested. The rFC method has been implemented at Sciensano for batch ...
Characterization and hazard identification of substandard and falsified antimicrobials encountered in Belgium
half of the samples were underdosed, resulting in a potential lower efficacy and so may aggravate illness of patients and induce bacterial resistance [2]. Moreover, in order to have an in-depth ...
The batch release procedure in Europe; manufacture and control of vaccine adjuvants; bacterial and polysaccharide vaccines
Publication Type: Scientific poster, presentation or proceeding Authors: L. Tesolin Source: ULB dept Pharmacy (2021) Health Topics: Effectiveness and safety of vaccines, medicines and health products- Quality of medical laboratories Efficacité et sécurit ...
The batch release procedure in Europe; Bacterial and polysaccharide vaccines
Publication Type: Scientific poster, presentation or proceeding Authors: L. Tesolin Source: ULB dept Pharmacy (2021) Health Topics: Effectiveness and safety of vaccines, medicines and health products- Quality of medical laboratories Efficacité et sécurit ...
Development and validation of a targeted LC-MS/MS quantitation method to monitor cell culture expression of tetanus neurotoxin during vaccine production
vaccine production. One of the major critical points in the manufacturing of these vaccines is the stable and reproducible production of high levels of toxin by the bacterial seed strains. In order to ...