Zoekresultaten - 5 results

Prioritizing substances of genotoxic concern for in-depth safety evaluation using non-animal approaches: The example of food contact materials.

Due to the exponentially growing number of substances requiring safety evaluation, efficient prioritisation strategies are needed to identify those of highest concern. To limit unnecessary animal ...

A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment

5 known positive and 5 known negative test compounds for genotoxicity was evaluated. In addition, 2 compounds with debatable genotoxicity data were tested to explore how the qPCR array would classify these. ...

(Q)SAR tools for priority setting: A case study with printed paper and board food contact material substances.

the combination of multiple (quantitative) structure-activity relationship ((Q) SAR) tools. Non-evaluated substances used in printed paper and board food contact materials (FCM) were selected for a case ...

Printed paper and board food contact materials as a potential source of food contamination.

(77%) considered non-evaluated in terms of potential toxicity. Based on a preliminary study of their physicochemical properties, it is estimated that most of the non-evaluated single substances have the ...

Evaluation of the migration of 15 photo-initiators from cardboard packaging into Tenax(®) using ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS).

Publication Type: Peer reviewed scientific article Authors: Kathy Van Den Houwe; van de Velde, S; Evrard, C; Els Van Hoeck; Joris Van Loco; Bolle, F Source: Food Addit Contam Part A Chem Anal Control Expo Risk Assess, Volume 31, Issue 4, p.767-75 (2014) K ...

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