Zoekresultaten - 19 results

Report on the feasibility of using Hi-C sequencing for metagenomics to define the context of AMR genes

Publication Type: Sci. report, recommendat°, guidance doc., directive, monograph Authors: Sigrid C.J. De Keersmaecker; Josephine Grützke; Carlus Deneke; Jennie Fischer; Lee Julia Bartsch; Bram Bloemen; Kevin Vanneste; Jolien D'aes; Nancy Roosens; Man ...

Genomic epidemiology of emerging ESBL-producing Kentucky in Europe.

Routine surveillance at the European Centre for Disease Prevention and Control (ECDC) detected cases with a ciprofloxacin-resistant. Kentucky with the ESBL-gene. Ensuing research identified 78 cases in ...

Deep amplicon sequencing for culture-free prediction of susceptibility or resistance to 13 anti-tuberculous drugs.

discordances involved gene deletions/indels and 3-12% heteroresistant calls undetected by WGS analysis, or natural pyrazinamide resistance of globally rare ” strains then unreported by Deeplex Myc- TB. On 1494 ...

Development of an NGS-Based Workflow for Improved Monitoring of Circulating Plasmids in Support of Risk Assessment of Antimicrobial Resistance Gene Dissemination.

Antibiotics (Basel), Volume 9, Issue 8 (2020) Keywords: Antimicrobial resistance MinION Plasmid sequencing Abstract: Antimicrobial resistance (AMR) is one of the most prominent public health threats. AMR genes ...

Molecular surveillance of anti-malarial drug resistance in Democratic Republic of Congo: high variability of chloroquinoresistance and lack of amodiaquinoresistance.

national policies as a first-line treatment for uncomplicated malaria in several endemic countries, such as the Democratic Republic of Congo (DRC). The K76T mutation on the pfcrt gene has been identified as ...

First detection of a plasmid located carbapenem resistant blaVIM-1 gene in E. coli isolated from meat products at retail in Belgium in 2015

Publication Type: Peer reviewed scientific article Authors: Cristina Garcia-Graells; Bas Berbers; Bavo Verhaegen; Kevin Vanneste; Marchal, Kathleen; Nancy Roosens; N Botteldoorn; Sigrid C.J. De Keersmaecker Source: International Journal of Food Microbiolo ...

RNA-based drug susceptibility testing of Mycobacterium tuberculosis

performed directly on crude cell lysate using a combination of the bead-based MagPixTM (Luminex) and QuantigeneTM Plex (Thermo Fischer) technology. Normalized, relative genes expression levels (control vs ...

Genetic Basis and Clonal Population Structure of Antibiotic Resistance in Isolated From Broiler Carcasses in Belgium.

quinolone resistance determining region (QRDR) of the gene, while isolates resistant to tetracycline were screened for the presence of the gene. These resistance determinants were observed in most but not all ...

Comparative genomics of quinolone-resistant and susceptible Campylobacter jejuni of poultry origin from major poultry producing European countries (GENCAMP)

different phylogenetic methods, ranging from single nucleotide polymorphisms analysis to gene-by-gene approaches such as rMLST, cgMLST, wgMLST and core genome tree, provided concordant results, but it is not ...

Nosocomial Intravascular Catheter Infections with Extended-spectrum Beta-lactamase-producing Escherichia coli in Calves after Strain Introduction from a Commercial Herd.

strains also overexpressed their chromosomal AmpC gene. Evidence on the introduction of the strain from a beef herd, experiencing neonatal diarrhoea and increased mortality, to the clinic through admission ...

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