Zoekresultaten - 67 results
Maintaining the quality of vaccines through the use of standards: Current challenges and future opportunities.
ever-increasing complexity, diversity, and number of vaccine products as well as increasing efforts to replace animal-based potency tests with in vitro assays that measure relevant quality attributes. As such, ...
Development of a monoclonal antibody sandwich ELISA for the determination of antigen content and quality in diphtheria vaccines.
testing and may be suitable to serve as the stability indicating test in replacement of the current in vivo potency test. Service: Qualité des vaccins et produits sanguins Kwaliteit van vaccins en ...
Towards Less Plastic in Food Contact Materials: An In-Depth Overview of the Belgian Market.
analysis was performed with an integrated web-based approach. Fifty-two sources were investigated, covering e-shops selling materials intended to replace disposable plastic materials or being advertised as ...
Rational arguments for regulatory acceptance of consistency testing: benefits of non-animal testing over release testing of vaccines.
Issue 1, Number 377 (2023) Abstract: INTRODUCTION: There are rational arguments to replace existing in vivo potency and safety assays for batch release testing of vaccines with more advanced non-animal ...
Targeted Chromosomal Barcoding Establishes Direct Genotype-Phenotype Associations for Antibiotic Resistance in Mycobacterium abscessus.
consisting of the specific replacement of the desired mutation in the bacterial chromosome. As surrogate bacteria, we used two M. abscessus bedaquiline-susceptible strains: ATCC 19977 and the SL541 clinical ...
Time trends in the use of field-substitution in the Belgian health interview survey
first round. During data-collection, non-participating households are replaced by substitute households, if needed up to seven times. In this manuscript, the use of field-substitution in the six rounds of ...
RE-Place: A Unique Project Collecting Expertise on New Approach Methodologies
Keywords: 3Rs animal testing Database Knowledge sharing NAMs new approach methodologies Open access RE-Place Abstract: By applying “New Approach Methodologies (NAM s)” based on innovative technologies such as ...
Ultrastable Silver Nanoparticles for Rapid Serology Detection of Anti-SARS-CoV-2 Immunoglobulins G.
in the case of real clinical samples, (ii) demonstrate that ultrastable calixarene-coated AgNPs could advantageously replace AuNPs in LFIA s, and thus (iii) open new perspectives in the field of rapid ...
Vaccine effectiveness against onward transmission of SARS-CoV2-infection by variant of concern and time since vaccination, Belgian contact tracing, 2021.
observed high vaccine effectiveness (VE) against SARS-CoV2-infection. The replacement of the alpha-‘variant of concern’ (VOC) by the delta- VOC and uncertainty about the time course of immunity called for ...
Evaluating Diagnostic Accuracy of Saliva Sampling Methods for Severe Acute Respiratory Syndrome Coronavirus 2 Reveals Differential Sensitivity and Association with Viral Load.
swabbing, respectively, regardless of symptomatic status. Our results suggest that saliva cannot readily replace nasopharyngeal sampling for SARS-CoV-2 diagnostics but may enable identification of the most ...