Zoekresultaten - 17 results
Characterisation and Hazard identification of substandard and Falsified Antimicrobial Drugs. The CantiBio project 2016-2020
comply with bio-burden testing, and one out of three injectable samples failed sterility testing with contamination of neurotoxin producing Penicillium crustosum. Moreover, it has been found that four out ...
The strategic change of the API fingerprint programme: from verification of authenticity of API sources to identifying potential quality issues
North-Macedonia (2024) Keywords: API GEON Quality Control Abstract: Since its creation the API-surveillance programme, performed under the hospices of the API-working group, focused a lot on the authenticity of API ...
Substandard and falsified ivermectin tablets obtained for self-medication during the COVID-19 pandemic as a source of potential harm.
at the end of 2020 and in 2021. Simultaneously, several reports started to emerge demonstrating serious adverse effects after self-medicating with ivermectin. It stands to reason that the ...
COMBINATION OF CHEMOMETRICS AND MULTIDIMENSIONAL FINGERPRINTING FOR DETECTION OF REGULATED PLANTS IN PLANT FOOD SUPPLEMENTS
Even though both models showed good correct classification rates (%), the multiclass model could give problems when two or more of the targeted plants are present, since it is only able to classify with ...
Multidimensional Chromatographic Fingerprinting Combined with Chemometrics for the Identification of Regulated Plants in Suspicious Plant Food Supplements.
approaches, but upon further comparison, binary models were preferred. As a proof of concept, the models were applied to twelve samples for the detection of four regulated plants. Overall, it was revealed that ...
Multidimensional Fingerprint Development for the Detection of Tribulus terrestris in Plant Food Supplements
of Tribulus in suspected samples. After obtaining MS fingerprints, the exact mass of the main peaks (peaks with the highest absorbance in the reference) were compared. It was concluded that out of 11 ...
CHROMATOGRAPHIC FINGERPRINT DEVELOPMENT FOR THE DETECTION OF TRIBULUS TERRESTRIS IN PLANT FOOD SUPPLEMENTS
spectrometry Results and conclusion: It was found and confirmed that 7 unknown samples showed the pres-ence of TT and more than half of it were confirmed for adulteration, i.e. adding TT without indication on ...
chromatographic fingerprinting for the detection of herbal adulteration and herbal fraud in plant food supplements
a series of plants it can become more tedious (Ichim, 2019). Here an approach is presented based on chromatographic fingerprinting and chemometrics to perform a targeted screening for three and two regulated ...
Relative response factors and multiple regression models in liquid chromatography to quantify low-dosed components using alternative standards-proof of concept: total Δ9-THC content in cannabis flowers using CBD as reference.
performed a comparison of the use of RRF s and linear relative response factor models (LRRFM) for the quantification of targeted low-dosed compounds using an alternative standard, since it is known that ...
OMCL testing and the API working group: Part of the solution?
manufacturers. Despite the efforts, API testing within the network is limited, compared to the surveillance of finished products. Though it has to be said that the risk for quality deficiencies and falsification ...