Zoekresultaten - 36 results
Potential business model for a European vaccine R&D infrastructure and its estimated socio-economic impact
Publication Type: Peer reviewed scientific article Authors: Jungbluth, Stefan; Martin, William; Slezak, Monika; Depraetere, Hilde; Guzman, Carlos A.; Ussi, Anton; Morrow, David; Van Heuverswyn, Fran; Arnouts, Sven; Carrondo, Manuel J. T.; Olesen, Ole; Ott ...
Vaccine effectiveness against onward transmission of SARS-CoV2-infection by variant of concern and time since vaccination, Belgian contact tracing, 2021.
infectiousness of breakthrough cases (VE i) for a complete schedule of Ad26. COV2.S, ChAdOx1, BNT162 b2, mRNA-1273 as well as infection-acquired and hybrid immunity. We used a multilevel Bayesian model and ...
Incidence and Risk Factors of COVID-19 Vaccine Breakthrough Infections: A Prospective Cohort Study in Belgium.
associated with breakthrough infections were analyzed using COX proportional hazard models. Among 8,062,600 fully vaccinated adults, we identified 373,070 breakthrough infections with an incidence of 11.2 (95% ...
Human challenge trial workshop: Focus on quality requirements for challenge agents, Langen, Germany, October 22, 2019.
Keywords: Biological Products Drug Development Human Experimentation Humans vaccines whole genome sequencing Abstract: Controlled human infection models can be helpful to study pathogenesis and immune ...
A new approach to define acceptance limits for hematology in external quality assessment schemes.
their corresponding assigned value (U-scores) was modeled by means of an adaptation of Thompson’s “characteristic function”. Quantile regression was used to investigate the percentiles of the U-scores for ...
Chemometrics and chromatographic fingerprints to classify plant food supplements according to the content of regulated plants.
objective way. Two approaches were followed: (1) a multiclass model, (2) 2-class model for each of the targeted plants separately. For both approaches good classification models were obtained, especially when ...
Detection of regulated herbs and plants in plant food supplements and traditional medicines using infrared spectroscopy.
combination of both. The results show that the screening of herbal preparations or plant food supplements for specific plants, using infrared spectroscopy, is feasible. The best model was obtained with the Mid- ...
Advanced Methods for Dose and Regimen Finding During Drug Development: Summary of the EMA/EFPIA Workshop on Dose Finding (London 4-5 December 2014).
for drug developers and regulators were presented. These methods are described in the present report: they include five advanced methods for data analysis (empirical regression models, pharmacometrics ...
Commentary on the MID3 Good Practices Paper.
Kerwash, Essam; Khan, David; Flora Musuamba Tshinanu; Ine Skottheim Rusten; EMA Modelling and Simulation Working Group Source: CPT Pharmacometrics Syst Pharmacol, Volume 6, Issue 7, p.416-417 (2017) ...
Zona pellucida gene mRNA expression in human oocytes is related to oocyte maturity, zona inner layer retardance and fertilization competence.
response resulted in a noninvasive oocyte fertilization prediction model. LARGE SCALE DATA: Not applicable. LIMITATIONS, REASONS FOR CAUTION: This is a retrospective study and the relation of oocyte mRNA ...