Zoekresultaten - 27 results
Spectroscopic approaches for conformity analysis of e-liquids
taurine, vitamin E and CBD in e-liquids. Therefore a set of 236 e-liquids was selected. Since samples with caffeine, taurine, CBD and vitamin E as additives were hard to find, some of the samples were split ...
Controlled Human Infection Studies: Proposals for guidance on how to design, develop and produce a challenge strain.
regulatory or advisory bodies. This document is intended to discuss fundamental principles of selection, characterization, manufacture, quality control and storage of challenge agents for international ...
Development of a multiplex immunoassay for simultaneous detection of antigens in DTaP vaccines
was carried out through in-depth monoclonal antibody characterization to determine the best antibody pairs to use in the antibody-antigen sandwich approach. Selected antibody pairs were used for ...
CBD oils on the Belgian market: A validated MRM GC-MS/MS method for routine quality control using QuEChERS sample clean up
method for the routine analysis of CBD oil samples. Eighteen CBD samples were selected on the Belgium market for analysis. This method allows the quantification of CBD, the legality check for the Δ9- THC ...
Identification of flavouring substances of genotoxic concern present in e-cigarette refills
transhexanal, there was a clear concern for in vivo genotoxicity. A selection of 4 out of the remaining 22 flavourings was tested in two in vitro genotoxicity assays. Three out of the four tested flavourings ...
Human challenge trial workshop: Focus on quality requirements for challenge agents, Langen, Germany, October 22, 2019.
challenge agents; a focus on strain selection, in particular with regard to strain infectivity, stability and purity; the use of whole genome sequencing; a reference repository of challenge agents, the need ...
Development and validation of chromatographic methods for screening and subsequent quantification of suspected illegal antimicrobial drugs encountered on the Belgian market.
agents, 1 antifungal agent and 1 beta-lactamase inhibitor, covering eleven different antibacterial classes, were selected. The UHPLC- MS screening method with gradient elution is able to selectively detect ...
Development and validation of chromatographic methods for screening and subsequent quantification of suspected illegal antimicrobial drugs encountered on the Belgian market
selected. The UHPLC- MS2 screening method with gradient elution is able to selectively detect these 36 compounds within 18 min (including wash and equilibration step). It was validated for sensitivity, ...
Analysis of illegal peptide drugs via HILIC-DAD-MS.
five different HILIC columns were selected and screened for their chromatographic performance. Among those columns, the ZIC HILIC column showed the best performance under the tested screening conditions ...
Detection of regulated herbs and plants in plant food supplements and traditional medicines using infrared spectroscopy.
misclassifications for the selected test set. For the other three a success rate of 50% was obtained. Mid- IR combined with SIMCA can therefore be applied as a first step in the screening of unknown samples, before ...