Zoekresultaten - 25 results
Use of Whole Genome Sequencing Data for a First in Silico Specificity Evaluation of the RT-qPCR Assays Used for SARS-CoV-2 Detection.
available, we used the bioinformatics tool SCREENED and a total of 4755 publicly available SARS-CoV-2 genomes, downloaded at two different time points, to evaluate the specificity of 12 RT-qPCR tests ...
Assessment of natural coagulants to remediate Tunisian textile wastewater by combining physicochemical, analytical, and toxicological data
effectiveness of the remediation treatments to remove potentially genotoxic compound(s). However, in the other genotoxicity tests, no biologically relevant effects were observed for any of the tested samples. In ...
Thyroid cancer incidence near nuclear sites in Belgium: An ecological study at small geographical level
sites. Focused hypothesis tests and generalized additive models were performed to test the hypothesis of a gradient in thyroid cancer incidence with increasing levels of surrogate exposures. No evidence ...
Opinion: Airtightness for Decontamination by Fumigation of High-Containment Laboratories
airtightness. Starting from a previous study in which we measured the airtightness in 4 BSL-3 laboratories with blower-door tests, we discuss the connection between airtightness and a successful decontamination ...
RE-Place: centralizing information on alternative methods to animal testing to promote knowledge sharing
Publication Type: Scientific poster, presentation or proceeding Authors: Mieke Van Mulders; Birgit Mertens; Rogiers, Vera Source: EUROTOX, Brussels, Belgium (2018) Keywords: 3R alternative methods Database in chemico In silico in vitro new approach method ...
Comparison of SNP-based subtyping workflows for bacterial isolates using WGS data, applied to Salmonella enterica serotype Typhimurium and serotype 1,4,[5],12:i:.
(low-coverage) datasets and two different reference genomes. All three tested workflows, namely CSI Phylogeny-based workflow, CFSAN-based workflow and PHE nix-based workflow, were able to correctly group the ...
A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment
regulatory accepted batteries for in vitro genotoxicity testing is recognized, they result in a high number of false positives. This has a major impact on society and industries developing novel compounds ...
RE-Place: Creation of a database for alternative methods to animal testing in the Flemish and Brussels region
Publication Type: Scientific poster, presentation or proceeding Authors: Mieke Van Mulders; Birgit Mertens; Rogiers, Vera Source: Knowledge For Growth, Issue FlandersBio, Ghent, Belgium (2018) Keywords: 3R alternative methods Database in chemico In silico ...
RE-Place: Alternative Methods to Animal Testing
Publication Type: Scientific poster, presentation or proceeding Authors: Mieke Van Mulders; Birgit Mertens; Rogiers, Vera Source: Tuesday Seminar, CODA-CERVA, Issue CODA-CERVA, Brussels, Belgium (2018) Keywords: 3R alternative methods Database in chemico ...
Childhood leukaemia near nuclear sites in Belgium, 2002–2008
with increasing levels of surrogate exposures was explored by means of focused hypothesis tests and generalized additive models. For the surrogate exposures, three proxies were used, that is, residential ...