- Bedoelde u
- exists
Zoekresultaten - 6 results
Assessing the receptor-mediated activity of PAHs using AhR-, ERα- and PPARγ- CALUX bioassays
agonistic and antagonistic endocrine activity of 9 environmentally relevant PAH s using three different CALUX bioassays: The AhR- CALUX, The ER α- CALUX and PPAR γ- CALUX. For the PPAR γ- CALUX anthracene, ...
Assessing the endocrine activity of PAHs using the DRE-, ERE- and PPARγ CALUX bioassays
pyrene and fluorene showed a weak agonistic activity for the PPAR y receptor. Only BaP showed a weak antagonistic activity. In both the agonistic and antagonistic tests, no effects were observed in ...
PKC epsilon-dependent calcium oscillations associated with metabotropic glutamate receptor 5 prevent agonist-mediated receptor desensitization in astrocytes.
nature of the calcium signals and the response regulation upon repeated exposures of astrocytes to the agonist (S)-3,5-dihydroxyphenylglycine. We show that upon repeated mGluR5 activations, a robust ...
Modulation de l’activité transcriptionelle de récepteurs nucléaires par les produits de migration de matériaux en plastique destinés aux jeunes enfants
activité sur aucun des récepteurs. La plupart des activités agonistes et antagonistes ont été observées respectivement sur le récepteur ER (29 substances sur 35) et PPAR y (20 substances sur 35). Aucune ...
Screening of endocrine activity of compounds migrating from plastic baby bottles using a multi-receptor panel of in vitro bioassays.
1mM. Only twelve chemicals did not show any activity towards any of the nuclear receptors, while fifty three compounds showed a possible endocrine activity. Most of the agonistic activities were observed ...
Innate signaling by mycobacterial cell wall components and relevance for development of adjuvants for subunit vaccines.
innate responses and contributing to the development of specific adaptive immune responses. Novel adjuvants have been developed based on agonists of PRR s. Areas covered: Lipid pathogen-associated ...