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Zoekresultaten - 5 results
Assessing the receptor-mediated activity of PAHs using AhR-, ERα- and PPARγ- CALUX bioassays
agonistic and antagonistic endocrine activity of 9 environmentally relevant PAH s using three different CALUX bioassays: The AhR- CALUX, The ER α- CALUX and PPAR γ- CALUX. For the PPAR γ- CALUX anthracene, ...
Modulation de l’activité transcriptionelle de récepteurs nucléaires par les produits de migration de matériaux en plastique destinés aux jeunes enfants
activité sur aucun des récepteurs. La plupart des activités agonistes et antagonistes ont été observées respectivement sur le récepteur ER (29 substances sur 35) et PPAR y (20 substances sur 35). Aucune ...
Screening of endocrine activity of compounds migrating from plastic baby bottles using a multi-receptor panel of in vitro bioassays.
1mM. Only twelve chemicals did not show any activity towards any of the nuclear receptors, while fifty three compounds showed a possible endocrine activity. Most of the agonistic activities were observed ...
In vitro endocrine activity of mycotoxins and their mixtures.
animals by influencing the synthesis, metabolism or transport of hormones; or by interacting directly with the hormone receptor (as an agonist or antagonist). Over the past decades there has been a growing ...
In vitro model to study the endocrine disrupting activity of migration products from plastic food contact materials
a recent study performed by Simoneau & al, 2012. Human estrogen receptor agonistic and antagonistic activities of 25 pure compounds were measured using MCF7- ER cells (genetically modified MCF7 cells). ...