Zoekresultaten - 10 results
Contribution of chronic conditions to gender disparities in health expectancies in Belgium, 2001, 2004 and 2008
2004: 5.6; 2008: 5.3) was observed in our cross- sectional approach followed by a decrease in gender differences in DFLE (2001: 1.9; 2004: 1.3; 2008: 0.5) and increase in LED (2001: 4.0; 2004: 4.4; 2008: ...
Quantifying burden of disease to support public health policy in Belgium: opportunities and constraints
DALY s were to be used for guiding health policy, a more systematic approach is required. By integrating DALY s in the current data generating systems, comparable estimates, rooted in recent local data, ...
Estimation of the dissociation rate of unlabelled ligand-receptor complexes by a 'two-step' competition binding approach.
APPROACH: We used the ‘two-step competition’ binding approach consisting of pre-incubating the receptor preparation with a wide range of ligand concentrations, washing off free ligand molecules, adding ...
Ligands, their receptors and... plasma membranes.
in cell membranes so that sufficiently lipophilic ligands could reach the receptor by a two-dimensional approach within the membrane. As summarized in this review, this may affect the ligand-receptor ...
Molecular mechanisms for the persistent bronchodilatory effect of the beta 2-adrenoceptor agonist salmeterol.
competing ligands. PURPOSE AND APPROACH: Computer-assisted simulations were performed to follow the receptor-occupation by a salmeterol-like ligand and a competing ligand as a function of time. The aptness of ...
Antagonist-radioligand binding to D2L-receptors in intact cells.
to compete with both radioligands. To integrate these new findings, a model is proposed in which raclopride approaches the receptor from the aqueous phase, while spiperone approaches the receptor by ...
Prioritisation of food-borne parasites in Europe, 2016.
Clinical Microbiology and Infectious Diseases. We used the same multicriteria decision analysis approach as the FAO / WHO, for comparison of results, and a modified version, for better regional ...
Perspectives on the integration of Immuno-Oncology Biomarkers and drugs in a Health Care setting.
their high cost with a significant economic impact on the health care system. These major challenges can likely be circumvented by implementing a “personalized immuno-oncology” approach to accomplish ...
Whole-genome-based phylogenomic analysis of the Belgian 2016-2017 influenza A(H3N2) outbreak season allows improved surveillance.
of all samples. A new approach, considering the whole genome, was investigated based on using powerful phylogenomic tools including beast and Nextstrain, which substantially improved phylogenetic ...
Optimization and Application of a Multiplex Digital PCR Assay for the Detection of SARS-CoV-2 Variants of Concern in Belgian Influent Wastewater.
low concentrations of SARS-CoV-2 RNA in IWW since the limit of detection of the different targets ranged between 0.3 and 2.9 copies/µL. This developed WBE approach was applied to IWW samples originating ...