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Zoekresultaten - 12 results
Modeling the migration of chemicals from food contact materials to food: The MERLIN-expo/VERMEER toolbox
Source: Food and Chemical Toxicology, Volume 166 (2022) Keywords: food contact material Migration model Uncertainty analysis Abstract: Evaluating the migration of chemicals from food contact materials (FCM) ...
Prioritizing substances of genotoxic concern for in-depth safety evaluation using non-animal approaches: The example of food contact materials.
of these are furthermore listed as a Substance of Very High Concern (SVHC) by the European Chemicals Agency (ECHA), in addition to demonstrating physicochemical properties linked to a high migration ...
Assessment of estrogenic compounds in paperboard for dry food packaging with the ERE-CALUX bioassay
Chemosphere, Volume 221, Number 106 (2019) Keywords: ERE-CALUX Estrogens FCM Food packaging; Paperboard Phthalates Abstract: Paperboard used as packaging, a non-inert material, can transfer chemicals into food. ...
A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment
for pharmaceutical, chemical, and consumer products, as afflicted compounds have to be (prematurely) abandoned or further tested on animals. Using the metabolically competent human HepaRG ™ cell line and toxicogenomics ...
Coatings in food contact materials: Potential source of genotoxic contaminants?
harmonized EU regulation exists on chemicals used in coatings for food contact materials (FCM). Therefore, these substances need to comply with the general provisions of EU Regulation 1935/2004 and, if ...
(Q)SAR tools for priority setting: A case study with printed paper and board food contact material substances.
Chemicals Paper Quantitative Structure-Activity Relationship SOFTWARE Abstract: Over the last years, more stringent safety requirements for an increasing number of chemicals across many regulatory fields ...
Printed paper and board food contact materials as a potential source of food contamination.
Importantly, 19 substances are also present in one of the lists with substances of concern compiled by the European Chemicals Agency (ECHA). To ensure consumer safety, the actual use of these substances in ...
Evaluation of the potential health risks of substances migrating from polycarbonate replacement baby bottles.
of (suspected) ED chemicals. Next, the potential non- ED risks were assessed. A distinction was made between migrants listed in Annex I of European Regulation 10/2011 and the unlisted substances (e.g. ...
Study of the possible migration risks of food contact materials for children under 3 years
simulant with a mixture of common organic compounds (Chapter 4.1) was optimised. To develop a robust and general method, a mixture of 17 chemicals (identified in the literature as possible migrants from FCM ...
Evaluation of the migration of chemicals from baby bottles under standardised and duration testing conditions.
microwaves milk Models, Chemical Nylons Plasticizers plastics Polyesters Polymers Polypropylenes Silicones Sterilization Sulfones Abstract: After the prohibition of bisphenol-A-containing polycarbonate baby ...