Zoekresultaten - 7 results

Urinary nicotine metabolites: usefulness as biomarkers of smoking status

and further to trans-3’-hydroxycotinine (HCOT) by the cytochrome P450 CYP2A6 enzyme. It has been demonstrated that the ratio of HCOT to COT is an index of CYP2A6 activity, thus a marker of nicotine ...

A Simultaneous D-Optimal Designed Study for Population Pharmacokinetic Analyses of Mycophenolic Acid and Tacrolimus Early After Renal Transplantation86

whereas first-order absorption with a lag time best described TAC transfer from the gastrointestinal tract. Parameters were estimated with good precision and accuracy. While hematocrit levels and CYP ...

Severe acute cardiomyopathy associated with venlafaxine overdose and possible role of CYP2D6 and CYP2C19 polymorphisms.

(Phila), Volume 49, Issue 9 (2011) Keywords: Adult Aryl Hydrocarbon Hydroxylases Cardiomyopathies Cyclohexanols Cytochrome P-450 CYP2C19 Cytochrome P-450 CYP2D6 Desvenlafaxine Succinate Drug Overdose Female ...

CYP3A5 and ABCB1 polymorphisms influence tacrolimus concentrations in peripheral blood mononuclear cells after renal transplantation.

Wallemacq, Pierre Source: Pharmacogenomics, Volume 11, Issue 5 (2010) Keywords: Adult ATP Binding Cassette Transporter, Subfamily B, Member 1 Blood Cells Clinical Laboratory Techniques Cytochrome P-450 CYP ...

Time of drug administration, CYP3A5 and ABCB1 genotypes, and analytical method influence tacrolimus pharmacokinetics: a population pharmacokinetic study92

Techniques,Analytical Chromatography,High Pressure Liquid Clinical Comparative Study Covariate Cytochrome P-450 CYP3A data de Demographic Demography Diagnostics DRUG Drug Administration Schedule Drug Monitoring effect ...

1199G> A and 2677G> T/A polymorphisms of ABCB1 independently affect tacrolimus concentration in hepatic tissue after liver transplantation.

1 Cytochrome P-450 CYP3A Cytochrome P-450 Enzyme System Drug Administration Schedule Gene Frequency Genotype Graft Rejection Humans Immunosuppressive Agents Linear Models Liver Liver Transplantation ...

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