Zoekresultaten - 849 results
M.tuberculosis mutants lacking oxygenated mycolates show increased immunogenicity and protective efficacy as compared to M. bovis BCG vaccine in an experimental mouse model.
Th1 (IFN-γ, IL-2 and TNF-α) and IL-17 responses could be induced following subcutaneous vaccination with either of the two mutants, than following vaccination with M. bovis BCG. Significantly more ...
In vitro and in vivo infectious potential of coxiella burnetii: a study on Belgian livestock isolates.
is a zoonosis caused by the gram-negative obligate intracellular pathogen Coxiella burnetii. Since its discovery, and particularly following the recent outbreaks in the Netherlands, C. burnetii ...
M2e-displaying virus-like particles with associated RNA promote T helper 1 type adaptive immunity against influenza A.
with similar particles lacking this domain, as deduced from the loss in body weight following challenge with X47 (H3N2) or PR /8 virus. Challenge of mice that had been immunized with M2 e- VLP s with or ...
A proteomics approach for the quantification of Staphylococcus aureus enterotoxins a and b in several matrices using uplc-msms analysis.
attributed to mixed or buffet meals (28.9%), followed by cheese (18.4%). This indicates that milk, milk derived products and ready-to-eat (RTI) foods require attention in detecting and quantifying SE s. We ...
End-of-life communication: a retrospective survey of representative general practitioner networks in four countries
were estimated per country. RESULTS: In total, 4396 nonsudden deaths were included. On average, more topics were discussed in The Netherlands (mean=6.37), followed by Belgium (4.45), Spain (3.32), and ...
Evidence for clinical applications of HR HPV testing.
NA (2013) Keywords: application applications at cancer cervix Clinical conference evidence Evidence-Based Medicine follow-up after treatment HPV meta-analysis primary screening Research triage Health ...
Clinical value of IS6110-based loop-mediated isothermal amplification for detection of Mycobacterium tuberculosis complex in respiratory specimens
or clinical recovery following anti- TB therapy was considered as a reference to prove the TB cases. RESULTS: The overall sensitivity of IS6110- LAMP, Amplicor, nPCR, and PCR were respectively 89.6% ...
Infections acquired in intensive care units: results of national surveillance in Belgium, 1997-2010.
surveillance programme. A protocol and software tool for data collection was developed, and the case definitions and methodology follow those of the European Centre for Disease Prevention and Control. FINDINGS: ...
Regulatory issues regarding manufacture and control of vaccine adjuvants. The EU situation.
on adjuvants describes all the quality requirements, where the adjuvant should fulfil to. Depending on the type of adjuvant, additional guidelines are in force and should be followed. Non clinical ...
Targeting the deep lungs, Poloxamer 407 and a CpG oligonucleotide optimize immune responses to Mycobacterium tuberculosis antigen 85A following pulmonary delivery34028
(CpG) to enhance immune responses to M. tuberculosis antigen 85A (Ag85A) following pulmonary delivery in BALB /c mice. An additional goal of this study was to localize the optimal delivery site of Ag85A ...