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Zoekresultaten - 5 results

Migration of mineral oil from cardboard packaging for food: Identification of the hazards and assessment of the exposure of the Belgian population

hazard-related information. Based on the margin of exposure (MOE) approach, there is no health concern related to MOSH exposure for the Belgian population. For MOAH, which may be potentially genotoxic and ...

Prioritizing substances of genotoxic concern for in-depth safety evaluation using non-animal approaches: The example of food contact materials.

printed paper and board food contact material (FCM) substances for further in-depth safety evaluation. Within the strategy, focus was put on genotoxicity, a key toxicological endpoint when evaluating ...

A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment

Keersmaecker; Rogiers, Vera; Tatyana Y. Doktorova Source: Archives of Toxicology (2018) Keywords: genotoxicity HepaRG In vitro screening mutagenicity qPCR array Toxicogenomics Abstract: Although the value of the ...

Coatings in food contact materials: Potential source of genotoxic contaminants?

human health. First, an inventory was assembled containing all substances potentially used in coatings. Afterwards, the genotoxic potential of the non-evaluated substances was predicted in silico using ...

Study of the possible migration risks of food contact materials for children under 3 years

process, the genotoxicity and endocrine activity of the identified migrants were evaluated by the partner universities participating in the ALTPOLYCARB project using a battery of in vitro assays. Chapter 5.1 ...

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