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Zoekresultaten - 5 results

Position paper on the use of an “estimated acceptable concentration” (EAC) as basis for a control policy's action level for carcinogens unintentionally present in food

Vleminckx; Van Huffel, Xavier; Peter Hoet Source: Trends in Food Science & Technology (2020) Keywords: Carcinogen Food safety management genotoxic ‘Margin of exposure’ (MOE) Abstract: Background In the ...

New QSAR models to predict chromosome damaging potential based on the in vivo micronucleus test

Emilio Source: Toxicology Letters, Volume 329, Number 84 (2020) Keywords: Chromosome damage genotoxicity In silico model In vivo micronucleus QSAR Abstract: A large number of computer-based prediction ...

Risk assessment of ochratoxin A in food

tumours in rodents. OTA is genotoxic both in vitro and in vivo; however, the mechanisms of genotoxicity are unclear. Direct and indirect genotoxic and non‐genotoxic modes of action might each contribute to ...

Risk assessment of aflatoxins in food

exposure. Aflatoxins are genotoxic and AFB1 can cause hepatocellular carcinomas (HCC s) in humans. The CONTAM Panel selected a benchmark dose lower confidence limit (BMDL) for a benchmark response of 10% of ...

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