Zoekresultaten - 20 results
Guidance in selecting analytical techniques for identification and quantification of non-intentionally added substances (NIAS) in food contact materials (FCMS)
plastics Abstract: There are numerous approaches and methodologies for assessing the identity and quantities of non-intentionally added substances (NIAS) in food contact materials (FCM s). They can give ...
Modeling the migration of chemicals from food contact materials to food: The MERLIN-expo/VERMEER toolbox
into food is a key step in the safety assessment of such materials. In this paper, a simple mechanistic model describing the migration of chemicals from FCM to food was combined with quantitative ...
Migration of mineral oil from cardboard packaging for food: Identification of the hazards and assessment of the exposure of the Belgian population
Bel; I Boonen; Els Van Hoeck Source: (2019) Accession Number: D/2019/14.440/8 Abstract: Mineral oil can enter the food via different routes. In order to obtain more insights in the extent of the mineral ...
Prioritizing substances of genotoxic concern for in-depth safety evaluation using non-animal approaches: The example of food contact materials.
testing, such strategies should respect the 3R principles (Replacement, Reduction, Refinement). In the present study, a strategy based on non-animal approaches was developed to prioritize non-evaluated ...
Assessment of estrogenic compounds in paperboard for dry food packaging with the ERE-CALUX bioassay
samples. Bis(2-ethylhexyl)phthalate (DEHP), dibutyl phthalate (DBP), butyl benzyl phthalate (BBP) and 1,2-cyclohexane dicarboxylic acid diisononyl ester (DINCH) were determined in all extraction and ...
A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment
Keersmaecker; Rogiers, Vera; Tatyana Y. Doktorova Source: Archives of Toxicology (2018) Keywords: genotoxicity HepaRG In vitro screening mutagenicity qPCR array Toxicogenomics Abstract: Although the value of the ...
Coatings in food contact materials: Potential source of genotoxic contaminants?
harmonized EU regulation exists on chemicals used in coatings for food contact materials (FCM). Therefore, these substances need to comply with the general provisions of EU Regulation 1935/2004 and, if ...
(Q)SAR tools for priority setting: A case study with printed paper and board food contact material substances.
(e.g. industrial chemicals, pharmaceuticals, food, cosmetics, …) have triggered the need for an efficient screening strategy to prioritize the substances of highest concern. In this context, alternative ...
Printed paper and board food contact materials as a potential source of food contamination.
and board FCM. In the current study, an inventory combining the substances which may be used in printed paper and board FCM, was created. More than 6000 unique compounds were identified, the majority ...
Evaluation of the potential health risks of substances migrating from polycarbonate replacement baby bottles.
prohibited the use of bisphenol A in the production of polycarbonate (PC) baby bottles, many other materials have replaced PC for the manufacture of this type of food contact materials. In the present study, ...