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Zoekresultaten - 176 results

In vitro endocrine activity of mycotoxins and their mixtures.

animals by influencing the synthesis, metabolism or transport of hormones; or by interacting directly with the hormone receptor (as an agonist or antagonist). Over the past decades there has been a growing ...

Biochemical analysis of the NAD+-dependent malate dehydrogenase, a substrate of several serine/threonine protein kinases of Mycobacterium tuberculosis

energy-supplying enzyme, catalyzes the interconversion of malate and oxaloacetate and plays crucial roles in several metabolic pathways including the citric acid cycle. The phosphorylation site was identified on ...

Genotoxicity testing of 3,4,5-trimethylfuran-2(5H)-one, a compound from plant-derived smoke with germination inhibitory activity.

(with/without S9 metabolic activation) and the cytome assay on human C3A cells, no genotoxicity or toxicity was found. Furthermore, these results support a previous study where a related smoke-derived compound ...

Functional elucidation of antibacterial phage ORFans targeting Pseudomonas aeruginosa

function Functional functions future gene Genes Genome identification im INFECTION interaction IS IT journal KNOWLEDGE metabolism Microscopy Molecular ON pattern protein Proteins Pseudomonas Pseudomonas ...

Systematic identification of hypothetical bacteriophage proteins targeting key protein complexes of pseudomonas aeruginosa

expressed genes of lytic bacteriophages, whose products are involved in the subversion of the host metabolism. In this study, we focused on the composition of important macromolecular complexes of Pseudomonas ...

Development of giant bacteriophage phiKZ is independent of the host transcription apparatus

Institute IS IT journal Laboratories map metabolism microbiology Molecular ON Operon Paper physiology protein Proteins Pseudomonas Pseudomonas aeruginosa Pseudomonas Phages Research Research Support Rna ...

Genotoxicity evaluation of nanosized titanium dioxide, synthetic amorphous silica and multi-walled carbon nanotubes in human lymphocytes.

metabolic activation), we observed significant increases in the frequencies of micronucleated binucleated cells (MNBC s) for some TiO2 NM s and for two MWCNT s, although no clear dose-response relationships ...

Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK651

electronic enzymology function functions Genetic genetics Glioblastoma growth Hand Hematology hospital Human Humans im in vivo IS IT journal Lipogenesis mechanism mechanisms medical metabolism Metformin mice ...

Use of Strep-tag II for rapid detection and purification of Mycobacterium tuberculosis recombinant antigens secreted by Streptomyces lividans

IS isolation & purification journal KNOWLEDGE M matrix MEDIA metabolism methods Mycobacterium Mycobacterium tuberculosis Oligopeptides Patient patients person present production protein Proteins ...

Urinary nicotine metabolites: usefulness as biomarkers of smoking status

metabolism, with higher ratios indicating faster metabolism. Evidence shows that the ratio, in urine, saliva or plasma, could predict responses to smoking cessation medication and guide pharmacotherapy. Since ...

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