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Zoekresultaten - 42 results
Increased vancomycin susceptibility in mycobacteria: a new approach to identify synergistic activity against multi-drug resistant mycobacteria36969
observed that glycopeptides strongly inhibited PDIM deprived mycobacteria. Vancomycin together with a drug targeting lipids synthesis inhibited multidrug-resistant (MDR) and extensively-drug resistant (XDR) ...
Biochemical analysis of the NAD+-dependent malate dehydrogenase, a substrate of several serine/threonine protein kinases of Mycobacterium tuberculosis
PknD-deficient mutant mycobacteria were grown in a phosphate-depleted medium, MDH was not detectably phosphorylated. These results suggest that although the MDH is a substrate of several mycobacterial STPK s, the ...
Evaluation of the Speed-Oligo Mycobacteria assay for the identification of nontuberculous mycobacteria.
Mycobacterium Infections, Nontuberculous Nontuberculous Mycobacteria Nucleic Acid Hybridization Oligonucleotides polymerase chain reaction Reagent Kits, Diagnostic RNA, Ribosomal, 16S Sensitivity and Specificity ...
The geographic diversity of nontuberculous mycobacteria isolated from pulmonary samples: an NTM-NET collaborative study36500
Laboratories List M Mycobacterium Mycobacterium avium Complex Network Nontuberculous Mycobacteria observed Patient patients Pulmonary relative result results Sample Samples SB- IM study Tuberculosis Abstract: ...
M.tuberculosis mutants lacking oxygenated mycolates show increased immunogenicity and protective efficacy as compared to M. bovis BCG vaccine in an experimental mouse model.
mycobacteria specific IFN-γ producing CD4 (+) and particularly CD8 (+) T cells could be detected by intracellular cytokine staining in mice vaccinated with the M.tb mutants. Finally, vaccination with either of ...
Urease activity represents an alternative pathway for Mycobacterium tuberculosis nitrogen metabolism31064
effect that helps neutralize the acidic microenvironment of the pathogen. In addition, urease serves as a nitrogen source provider for bacterial growth. Pathogenic mycobacteria express a functional urease ...
Amoebae as potential environmental hosts for Mycobacterium ulcerans and other mycobacteria, but doubtful actors in Buruli ulcer epidemiology36450
Furthermore, we collected 13 water, 90 biofilm and 45 detritus samples in both Buruli ulcer endemic and non-endemic communities in Ghana, from which we cultivated amoeboid protozoa and mycobacteria. M. ulcerans ...
Buruli ulcer
other mycobacteria, e.g. M. tuberculosis, while other targets are unique to M. ulcerans. In this review, we discuss several M. ulcerans vaccine targets and vaccination methods, and outline some of the ...
T cell reactivity against mycolyl transferase antigen 85 of M. tuberculosis in HIV-TB coinfected subjects and in AIDS patients suffering from tuberculosis and nontuberculous mycobacterial infections
Mycobacterium Mycobacterium Infections Mycobacterium tuberculosis Nontuberculous Mycobacteria Patient patients physiology protein Research Research Support response Responses SB- IM Switzerland Symptom Symptoms ...
Biochemical and immunological characterization of a cpn60.1 knockout mutant of Mycobacterium bovis BCG1265
Pathogenic mycobacteria possess two homologous chaperones encoded by cpn60.1 and cpn60.2. Cpn60.2 is essential for survival, providing the basic chaperone function, while Cpn60.1 is not. In the present study ...