Zoekresultaten - 106 results

Applicability of the DPRA on mixture testing: challenges and opportunities.

Keywords: Animal Testing Alternatives Animals Peptides Abstract: The in chemico direct peptide reactivity assay (DPRA) is validated to assess protein reactivity of chemical compounds, relating to the ...

From b to y ions, a decade of experience with peptide and protein analysis

recombinant expression technologies, and peptide synthesis have led to an increased development of protein and peptide therapeutics. Due to improved and simplified manufacturing techniques, disregard for patent ...

Humoral and cellular immune responses against SARS-CoV-2 after third dose BNT162b2 following double-dose vaccination with BNT162b2 versus ChAdOx1 in cancer patients.

SARS-CoV-2 specific S1 and S2  peptides. RESULTS: Local AE s were more common after heterologous boosting. SARS-CoV-2 anti- S1 IgG antibody levels did not differ significantly between homologous and ...

Predictive model for BNT162b2 vaccine response in cancer patients based on blood cytokines and growth factors.

Volume 13 (2022) Keywords: BNT162 Vaccine COVID-19 Cytokines Female Humans Intercellular Signaling Peptides and Proteins Neoplasms Placenta Growth Factor vaccines Abstract: BACKGROUND: Patients with ...

Development, Validation and Application of a Targeted LC-MS Method for Quantification of Microcystins and Nodularin: Towards a Better Characterization of Drinking Water

(ADDA) group connected to a peptide ring. However, NOD ’s ring contains five peptides, whereas the MC s have a heptacyclic peptide ring [13,14]. Both toxins inhibit protein phosphatase 1 (PPI) and 2A ...

Pharmacokinetics of Oral Rebaudioside A in Patients with Type 2 Diabetes Mellitus and Its Effects on Glucose Homeostasis: A Placebo-Controlled Crossover Trial

− 22.3; 20.9) h·mg/dL, P = 0.95). Insulin and C-peptide concentrations were also comparable between both conditions (P > 0.05). Conclusion Rebaudioside A is readily absorbed after oral administration and ...

The bacteriophage LUZ24 "Igy" peptide inhibits the Pseudomonas DNA gyrase.

are proving problematic. Here, we describe Igy, a peptide inhibitor of gyrase, encoded by Pseudomonas bacteriophage LUZ24 and other members of the Bruynoghevirus genus. Igy (5.6 kDa) inhibits in vitro ...

Application of the direct peptide reactivity assay to mixtures of sensitizing compounds

Publication Type: Dissertation Authors: Rama Ghazal; Tamara Vanhaecke; Quinten Marcelis; Bart Desmedt Source: VUB, Brussels, Belgium, p.71 (2021) Health Topics:  Allergene geurstoffen Parfums allergisants Fragrance allergens Manuscript versions:  DOI:  ht ...

Functional Analysis of Human and Feline Coronavirus Cross-Reactive Antibodies Directed Against the SARS-CoV-2 Fusion Peptide.

Viral Antigens, Viral Blood Donors Cats Chlorocebus aethiops Coronavirus, Feline COVID-19 COVID-19 Serological Testing Cross Reactions Epitopes Humans Pandemics Peptides SARS-CoV-2 Spike Glycoprotein, ...

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