Zoekresultaten - 40 results
Advanced Methods for Dose and Regimen Finding During Drug Development: Summary of the EMA/EFPIA Workshop on Dose Finding (London 4-5 December 2014).
and adaptive studies). Pairwise comparisons were also discussed during the workshop; however, mostly for historical reasons. This paper discusses the added value and limitations of these methods as well ...
Characterization of suspected dermal fillers containing hyaluronic acid
During the validation a variety of formulations including those present in legal HA containing dermal fillers were taken into consideration. As a proof of principle, legal and suspected illegal dermal ...
Zona pellucida gene mRNA expression in human oocytes is related to oocyte maturity, zona inner layer retardance and fertilization competence.
Presence of ZP3 protein in CC and oocytes was investigated using immunocytochemistry. Data were analysed using one-parametric and multivariate analysis and were corrected for the potential impact of patient ...
The ADVANCE Code of Conduct for collaborative vaccine studies.
report and publications and journal editors are encouraged to use it as an indication that good principles of public health, science and transparency were followed throughout the study. Health Topics: ...
Chromatographic fingerprinting as a strategy to identify regulated plants in illegal herbal supplements.
explore the potential use of chromatographic fingerprinting to identify plants present in herbal preparations intended for the treatment of ED. To achieve this goal, a HPLC- PDA and a HPLC- MS method were ...
An application of mass spectrometry for quality control of biologicals: Highly sensitive profiling of plasma residuals in human plasma-derived immunoglobulin.
Without any prior information or target-specific development, >30 proteins were identified in a commercial Ig product. Quality control relevance was demonstrated with the identification of FXI a spiked ...
The fate of buccal bone around dental implants. A 12-month postloading follow-up study.
measurements without the elevation of a muco-periostal flap. These measurements were repeated after 12 months of loading. Sixteen implants were placed flapless and 31 with the elevation of a flap. Of the latter, ...
Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective.
to implement testing of human in vitro alternatives to animal testing. Health Topics: Effectiveness and safety of vaccines, medicines and health products- Quality of medical laboratories Category: A1 ...
Childhood leukaemia near nuclear sites in Belgium, 2002-2008.
three proxies were used, that is, residential proximity to the nuclear site, prevailing winds and simulated radioactive discharges, on the basis of mathematical dispersion modelling. No excess incidence ...
Chromatographic impurity fingerprinting of genuine and counterfeit Cialis® as a means to compare the discriminating ability of PDA and MS detection.
by counterfeit medicines. Their quality, safety and efficacy cannot be guaranteed since no quality control is performed during and/or after the manufacturing process. Characterization of these products ...